ArticleJournal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology2008
Effects of stimulation frequency versus pulse duration modulation on muscle fatigue.
Article in Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06127602 (NeuroMuscular Electrical Stimulation to Facilitate Perturbation-based REACtive Balance Training for Fall Risk Reduction Post-stroke), which is not on this map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NeuroMuscular Electrical Stimulation to Facilitate Perturbation-based REACtive Balance Training for Fall Risk Reduction Post-stroke: The REACTplusNMES Trial
Who cites it
39 citing papers in PubMed.
- Effect of Russian current expert modes on quadriceps muscle torque in healthy adults: A single-blinded randomized controlled trial.PloS one · 2024Trial
- Impact of stimulation frequency on neuromuscular fatigue.European journal of applied physiology · 2019Trial
- The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults.Dysphagia · 2019Trial
- Is electrical stimulation beneficial for improving the paralytic effect of botulinum toxin type A in children with spastic diplegic cerebral palsy?Yonsei medical journal · 2008Trial
- The role of pulse duration and stimulation duration in maximizing the normalized torque during neuromuscular electrical stimulation.The Journal of orthopaedic and sports physical therapy · 2008Trial
- Repetitive Grasping After Stroke Assisted by Functional Electrical Stimulation.Artificial organs · 2025Observational
- Development of an electrical current stimulator for controlling biohybrid machines.Scientific reports · 2025Article
- Reinforcement Learning Agent Trained as FES Controller in Modified Xia-Law Simulation Robustly Controls Grip Force.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Optimizing electrical field stimulation parameters reveals the maximum contractile function of human skeletal muscle microtissues.American journal of physiology. Cell physiology · 2025Article
- Optimal neuromuscular electrical stimulation parameters after spinal cord injury.The journal of spinal cord medicine · 2024Article
- Fully implanted battery-free high power platform for chronic spinal and muscular functional electrical stimulation.Nature communications · 2023Article
- Contributions of the Cybathlon championship to the literature on functional electrical stimulation cycling among individuals with spinal cord injury: A bibliometric review.Journal of sport and health science · 2022Review
- Accelerating peripheral nerve regeneration using electrical stimulation of selected power spectral densities.Neural regeneration research · 2022Article
- An Optimal Transport Based Transferable System for Detection of Erroneous Somato-Sensory Feedback from Neural Signals.Brain sciences · 2021Article
- Noninvasive spinal stimulation safely enables upright posture in children with spinal cord injury.Nature communications · 2021Article
- A Flexible Pulse Generator Based on a Field Programmable Gate Array Architecture for Functional Electrical Stimulation.Frontiers in neuroscience · 2021Article
- Advances in neuroprosthetic management of foot drop: a review.Journal of neuroengineering and rehabilitation · 2020Review
- Stimulation of paralysed quadriceps muscles with sequentially and spatially distributed electrodes during dynamic knee extension.Journal of neuroengineering and rehabilitation · 2019Article
- Mitigation of excessive fatigue associated with functional electrical stimulation.Journal of neural engineering · 2018Article
- Effect of neuromuscular electrical stimulation frequency on muscles of the tongue.Muscle & nerve · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
During functional electrical stimulation (FES), both the frequency and intensity can be increased to increase muscle force output and counteract the effects of muscle fatigue. Most current FES systems, however, deliver a constant frequency and only vary the stimulation intensity to control muscle force. This study compared muscle performance and fatigue produced during repetitive electrical stimulation using three different strategies: (1) constant pulse-duration and stepwise increases in frequency (frequency-modulation); (2) constant frequency and stepwise increases in pulse-duration (pulse-duration-modulation); and (3) constant frequency and pulse-duration (no-modulation). Surface electrical stimulation was delivered to the quadriceps femoris muscles of 12 healthy individuals and isometric forces were recorded. Muscle performance was assessed by measuring the percent changes in the peak forces and force-time integrals between the first and the last fatiguing trains. Muscle fatigue was assessed by measuring percent declines in peak force between the 60Hz pre- and post-fatigue testing trains. The results showed that frequency-modulation showed better performance for both peak forces and force-time integrals in response to the fatiguing trains than pulse-duration-modulation, while producing similar levels of muscle fatigue. Although frequency-modulation is not commonly used during FES, clinicians should consider this strategy to improve muscle performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.