Evidence map›Paper›PMID 17316540›Full record

ArticleAnalytical biochemistry2007

Metal particle-enhanced fluorescent immunoassays on metal mirrors.

Evgenia G Matveeva, Ignacy Gryczynski, Anne Barnett, Zoya Leonenko, Joseph R Lakowicz, Zygmunt Gryczynski

Open access · greenAbstract read
In one paragraph

Article in Analytical biochemistry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 86 citations in OpenAlex.

  1. Review
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  9. Article
  10. Fabrication and Characterization of Planar Plasmonic Substrates with High Fluorescence Enhancement.The journal of physical chemistry. C, Nanomaterials and interfaces · 2010
    Article
  11. Time-Resolved Fluorometric Method for One-Step Immunoassays Using Plasmonic Nanostructures.The journal of physical chemistry. C, Nanomaterials and interfaces · 2010
    Article
  12. Article
  13. Plasmon-controlled fluorescence towards high-sensitivity optical sensing.Advances in biochemical engineering/biotechnology · 2009
    Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Evgenia G MatveevaDepartment of Molecular Biology and Immunology, Health Science Center, University of North Texas, Fort Worth, TX 76107, USA. ematveev@hsc.unt.edu <ematveev@hsc.unt.edu>
Ignacy Gryczynski
Anne Barnett
Zoya Leonenko
Joseph R Lakowicz
Zygmunt Gryczynski
University of Maryland, Baltimore · USUniversity of North Texas · USUniversity of North Texas Health Science Center · US

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
SPCE Imaging MicroscopyR33CA114460 · NCI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GRYCZYNSKI, IGNACY · 2005 to 2006
$379k
Fluorophore-Metallic Colloid Conjugates for Medical ImagR33EB001690 · NIBIB · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GRYCZYNSKI, ZYGMUNT · 2005 to 2006
$304k
Fluorophore-Metallic Colloid Conjugates for Medical ImagR21EB001690 · NIBIB · UNIVERSITY OF MARYLAND BALTIMORE · PI GRYCZYNSKI, ZYGMUNT · 2003 to 2003
$121k
NCI NIH HHS CA 114460NCI NIH HHS R33 CA114460NCRR NIH HHS P41 RR008119NIBIB NIH HHS EB-1690NIBIB NIH HHS R21 EB001690NIBIB NIH HHS R33 EB001690PHS HHS NCRR-08119
6 · The paper itself

Abstract

We present fluoroimmunoassays on plain metal-coated surfaces (metal mirrors) enhanced by metal nanoparticles (silver island films [SIFs]). Metal mirrors (aluminum, gold, or silver protected with a thin silica layer) were coated with SIFs, and an immunoassay (model assay for rabbit immunoglobulin G or myoglobin immunoassay) was performed on this surface using fluorescently labeled antibodies. Our results showed that SIFs alone (on glass surface not coated with metal) enhance the immunoassay signal approximately 3- to 10-fold. Using a metal mirror instead of glass as support for SIFs results in up to 50-fold signal enhancement.

Indexed as

AnimalsFluoroimmunoassayImmunoglobulin GMetal NanoparticlesMetalsMicroscopy, Atomic ForceModels, TheoreticalMyoglobinNanotechnologyRabbitsReproducibility of ResultsSilverImmunoglobulin GMetalsMyoglobinSilver

Identifiers

PMID17316540
PMCPMC6814007
OpenAlexW2043352587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.