Evidence map›Paper›PMID 17315402›Full record

ArticleVascular health and risk management2005

Fasting serum triglyceride and high-density lipoprotein cholesterol levels in patients intended to be treated for dyslipidemia.

Genovefa D Kolovou, Katherine Anagnostopoulou, Nektarios D Pilatis, Klelia D Salpea, Ioannis S Hoursalas, Ilias Petropoulos, Helen I Bilianou, Dennis V Cokkinos

Abstract readComparative Study
In one paragraph

Article in Vascular health and risk management, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Genovefa D KolovouCardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. genkolovou@mail.gr
Katherine Anagnostopoulou
Nektarios D Pilatis
Klelia D Salpea
Ioannis S Hoursalas
Ilias Petropoulos
Helen I Bilianou
Dennis V Cokkinos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present investigation was to evaluate the influence of serum triglycerides (TG) on other plasma lipids in patients to be treated for dyslipidemia. METHODOLOGY: Lipid profiles of a cohort of 801 patients (487 males and 314 females) aged 57 +/- 9 years (mean +/- SD) were evaluated. Patients were stratified according to their plasma lipid levels. They were divided into various groups on the basis of serum TG (> or = 150 or < 150 mg/dL) and high-density lipoprotein cholesterol (HDL-C) (> or = 40 or < 40 mg/dL).

resultsPatients with TG > or = 150 mg/dL had a higher total cholesterol and lower HDL-C levels compared with those with TG < 150 mg/dL, (p < 0.001). Patients with HDL-C < 40 mg/dL had a lower serum total cholesterol and higher TG compared with those with HDL-C > or = 40 mg/dL (p = 0.011 and p < 0.0001, respectively). In all patients as well as in the subgroups, an inverse correlation between TG and HDL-C was found (r = -0.377, p < 0.001).

conclusionsAlthough, the metabolic pathway for TG and HDL-C is closely linked, an inverse correlation between TG and HDL-C levels seems to exist in the entire sampled population. This correlation also appears to persist in fasting patients with low levels of TG.

Indexed as

CholesterolCholesterol, HDLCohort StudiesDyslipidemiasFastingFemaleHumansHypolipidemic AgentsMaleMiddle AgedTriglyceridesCholesterolCholesterol, HDLHypolipidemic AgentsTriglycerides

Identifiers

PMID17315402
PMCPMC1993943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.