Evidence map›Paper›PMID 17314227›Full record

ArticleJournal of clinical microbiology2007

Clonal distribution of invasive Neisseria meningitidis serogroup C strains circulating from 1976 to 2005 in greater Sao Paulo, Brazil.

Ana Paula Silva de Lemos, Teresa Ykuko Yara, Maria Cecília Outeiro Gorla, Maria Vaneide de Paiva, Adriana Lambert de Souza, Maria Inês Cappelletti Gonçalves, Samanta Cristine Grassi de Almeida, Gloria Regina Feitas do Valle, Claudio Tavares Sacchi

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 51 citations in OpenAlex.

  1. Phenotypic characterization ofAccess microbiology · 2020
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  3. Observational
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  5. Review
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  14. A cross-sectional study assessing the pharyngeal carriage of Neisseria meningitidis in subjects aged 1-24 years in the city of Embu das Artes, São Paulo, Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
  15. Meningococcal disease before and after the introduction of meningococcal serogroup C conjugate vaccine. Federal District, Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ana Paula Silva de LemosInstituto Adolfo Lutz, Av. Dr. Arnaldo, 351 9 andar, São Paulo 01246-900, Brazil. apaula@ial.sp.gov.br
Teresa Ykuko Yara
Maria Cecília Outeiro Gorla
Maria Vaneide de Paiva
Adriana Lambert de Souza
Maria Inês Cappelletti Gonçalves
Samanta Cristine Grassi de Almeida
Gloria Regina Feitas do Valle
Claudio Tavares Sacchi
Instituto Adolfo Lutz · BRGoverno do Estado de São Paulo · BR

Funding

Real-Time PCR for Diagnosis of Culture-Negative Bacterial Meningitis in S?o PauloD43TW006592 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2004 to 2013
$1.7M
FIC NIH HHS 5D43TW006592FIC NIH HHS D43 TW006592
6 · The paper itself

Abstract

Meningococcal disease is characterized by cyclic fluctuations in incidence, serogroup distribution, and antigenic profiles. In greater São Paulo, Brazil, there has been a constant increase in the incidence of serogroup C meningococcal disease since the late 1980s. To gain an understanding of changes in serogroup C meningococcal disease over three decades in greater São Paulo, Brazil, 1,059 invasive Neisseria meningitidis serogroup C isolates from 1976 and 2005 were analyzed. Three major clone complexes, sequence type (ST)-11, ST-8, and ST-103, were identified by multilocus sequence typing, and the isolates were characterized by serotyping and 16S rRNA typing. During the 30-year period, there were two major antigenic replacements: from 2a:P1.(5,2) to 2b:P1.3 and subsequently to 23:P1.14-6. All strains of clone ST-103 were characterized as serotype 23 and serosubtype P1.14-6. The origin of 23:P1.14-6 ST-103 complex strains is unknown, but efforts are needed to monitor its spread and define its virulence. The antigenic replacements we observed likely represent a mechanism to sustain meningococcal disease in the population as immunity to circulating strains accumulated.

Indexed as

Antigens, BacterialBrazilDNA, BacterialDNA, RibosomalEvolution, MolecularHumansMeningitis, MeningococcalMolecular EpidemiologyMolecular Sequence DataNeisseria meningitidis, Serogroup CRNA, Ribosomal, 16SSerotypingAntigens, BacterialDNA, BacterialDNA, RibosomalRNA, Ribosomal, 16S

Identifiers

PMID17314227
PMCPMC1865849
OpenAlexW2113089815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.