Evidence map›Paper›PMID 17313697›Full record

ArticleEpidemiology and infection2008

Structured surveillance of infantile gastroenteritis in East Anglia, UK: incidence of infection with common viral gastroenteric pathogens.

M Iturriza Gómara, R Simpson, A M Perault, C Redpath, P Lorgelly, D Joshi, M Mugford, C A Hughes, J Dalrymple, U Desselberger and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Impact of rotavirus vaccination on rotavirus genotype distribution and diversity in England, September 2006 to August 2016.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
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  9. Review
  10. Diagnosis of viral gastroenteritis in children: interpretation of real-time PCR results and relation to clinical symptoms.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Review
  11. Article
  12. Climate Change Impact Assessment of Food- and Waterborne Diseases.Critical reviews in environmental science and technology · 2012
    Article
  13. Article
  14. Article
  15. Review
  16. Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2011
    Article
  17. Article
  18. Article
  19. Viral gastroenteritis.Medicine (Abingdon, England : UK ed.) · 2009
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

M Iturriza GómaraEnteric Virus Unit, Virus Reference Department, Centre for Infections, Health Protection Agency, London, UK. miren.iturriza@hpa.org.uk
R Simpson
A M Perault
C Redpath
P Lorgelly
D Joshi
M Mugford
C A Hughes
J Dalrymple
U Desselberger
J Gray
Addenbrooke's Hospital · GBUniversity of East Anglia · GBNorfolk and Suffolk NHS Foundation Trust · GBPublic Health England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the burden of disease associated with gastroenteric viruses (rotavirus, norovirus, sapovirus, astrovirus and enteric adenovirus) using structured surveillance of children aged <6 years in the community. Faecal samples were collected between 2000 and 2003 from 685 children with symptoms of gastroenteritis. The children comprised three groups; 223 in the structured surveillance cohort, 203 in a community cohort and 259 in a cohort of hospitalized children. All samples were tested for the presence of viral pathogens using molecular methods. Questionnaires were sent to the parents/carers of the children recruited to the structured surveillance cohort in order to collect data that would allow an estimation of the severity of illness by means of the Vesikari score, and of the cost associated with gastrointestinal disease in this age group. A viral aetiological agent was detected in 53.5% of samples tested. Rotavirus was the most common pathogen found in all three cohorts followed by norovirus and enteric adenoviruses. Multiple viruses were found in 8% of the samples, and commonly involved rotavirus and any other virus. G1P[8] was the most commonly detected rotavirus strain and there was no significant difference in the distribution of rotavirus genotypes among the three cohorts. Analysis of the questionnaires indicated that rotavirus infections were likely to be more severe than any other virus infection, and children from whom a viral pathogen was identified were more likely to require rehydration therapy.

Indexed as

ChildChild, HospitalizedChild, PreschoolCohort StudiesDiarrhea, InfantileDNA, ViralEnglandFecesGastroenteritisHumansIncidenceInfantInfant, NewbornPolymerase Chain ReactionPopulation SurveillanceRotavirusDNA, Viral

Identifiers

PMID17313697
PMCPMC2870758
OpenAlexW2162917258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.