Evidence map›Paper›PMID 17313320›Full record

ReviewAnnual review of nutrition2007

Regulation of lipolysis in adipocytes.

Robin E Duncan, Maryam Ahmadian, Kathy Jaworski, Eszter Sarkadi-Nagy, Hei Sook Sul

Abstract readReview
In one paragraph

Review in Annual review of nutrition, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 491 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
491citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

491 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Changes in Ghrelin and Glucagon following a Low Glycemic Load Diet in Women with PCOS.The Journal of clinical endocrinology and metabolism · 2021
    Trial
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  7. Exercise and Fat: A Primer.Sports medicine - open · 2026
    Review
  8. Review
  9. Article
  10. How organs react under fasting or glucose-insulin status: a self-controlled study usingEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

431 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robin E DuncanDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, CA 94720, USA.
Maryam Ahmadian
Kathy Jaworski
Eszter Sarkadi-Nagy
Hei Sook Sul

Funding

Role of desnutrin/ATGL in maintenance and function of brown adipose tissueR01DK093928 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI SUL, HEI SOOK · 2012 to 2015
$1.3M
Novel adipocyte-specific enzymes in triacylglycerol metabolismR01DK075682 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI SUL, HEI SOOK · 2006 to 2009
$1.1M
NIDDK NIH HHS R01 DK075682NIDDK NIH HHS R01 DK093928
6 · The paper itself

Abstract

Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and nonesterified fatty acids that are released into the vasculature for use by other organs as energy substrates. In response to changes in nutritional state, lipolysis rates are precisely regulated through hormonal and biochemical signals. These signals modulate the activity of lipolytic enzymes and accessory proteins, allowing for maximal responsiveness of adipose tissue to changes in energy requirements and availability. Recently, a number of novel adipocyte triacylglyceride lipases have been identified, including desnutrin/ATGL, greatly expanding our understanding of adipocyte lipolysis. We have also begun to better appreciate the role of a number of nonenzymatic proteins that are critical to triacylglyceride breakdown. This review provides an overview of key mediators of lipolysis and the regulation of this process by changes in nutritional status and nutrient intakes.

Indexed as

Nutritional StatusSignal TransductionAdipocytesAnimalsHormonesHumansLipaseLipolysisTriglyceridesHormonesLipaseTriglycerides

Identifiers

PMID17313320
PMCPMC2885771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.