Evidence map›Paper›PMID 17309907›Full record

Trial reportHeart (British Cardiac Society)2007

Disease management programme for secondary prevention of coronary heart disease and heart failure in primary care: a cluster randomised controlled trial.

Kamlesh Khunti, Margaret Stone, Sanjoy Paul, Jan Baines, Louise Gisborne, Azhar Farooqi, Xiujie Luan, Iain Squire

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Heart (British Cardiac Society), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03428061 (The ZWOlle Transmural Integrated Care for CArdiovaScular Risk Management Study), which is not on this map. Cited by 30 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 7 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03428061 unknown statusnot on this mapstarted 2017, after this paper: background citation

The ZWOlle Transmural Integrated Care for CArdiovaScular Risk Management Study

TypeobservationalSponsorUMC UtrechtRan2017 to 2018Enrolled740ConditionsCardiovascular Diseases, Hypercholesterolemia, HypertensionArmsIntegrated care for cardiovascular risk management
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Disease management interventions for heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
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  3. Patient education in the management of coronary heart disease.The Cochrane database of systematic reviews · 2017
    Pooled it
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  8. Diagnosis and management of sleep apnea by a clinical nurse: a noninferiority randomized clinical trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
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  11. Effectiveness of nurse-delivered cardiovascular risk management in primary care: a randomised trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kamlesh KhuntiDepartment of Health Sciences, University of Leicester, UK. kk22@le.ac.uk
Margaret Stone
Sanjoy Paul
Jan Baines
Louise Gisborne
Azhar Farooqi
Xiujie Luan
Iain Squire
University of Leicester · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate the effect of a disease management programme for patients with coronary heart disease (CHD) and chronic heart failure (CHF) in primary care.

methodsA cluster randomised controlled trial of 1316 patients with CHD and CHF from 20 primary care practices in the UK was carried out. Care in the intervention practices was delivered by specialist nurses trained in the management of patients with CHD and CHF. Usual care was delivered by the primary healthcare team in the control practices.

resultsAt follow up, significantly more patients with a history of myocardial infarction in the intervention group were prescribed a beta-blocker compared to the control group (adjusted OR 1.43, 95% CI 1.19 to 1.99). Significantly more patients with CHD in the intervention group had adequate management of their blood pressure (<140/85 mm Hg) (OR 1.61, 95% CI 1.22 to 2.13) and their cholesterol (<5 mmol/l) (OR 1.58, 95% CI 1.05 to 2.37) compared to those in the control group. Significantly more patients with an unconfirmed diagnosis of CHF had a diagnosis of left ventricular systolic dysfunction confirmed (OR 4.69, 95% CI 1.88 to 11.66) or excluded (OR 3.80, 95% CI 1.50 to 9.64) in the intervention group compared to the control group. There were significant improvements in some quality-of-life measures in patients with CHD in the intervention group.

conclusionsDisease management programmes can lead to improvements in the care of patients with CHD and presumed CHF in primary care.

Indexed as

Disease ManagementAdrenergic beta-AntagonistsAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsBlood PressureCholesterolCoronary DiseaseDrug UtilizationEnglandFemaleHeart FailureHumansHypolipidemic AgentsMaleMiddle AgedAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsCholesterolHypolipidemic Agents

Identifiers

PMID17309907
PMCPMC2016933
OpenAlexW2167115274

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.