Evidence map›Paper›PMID 17303981›Full record

ArticleBlood pressure monitoring2007

Reliability and validity of blood pressure measurement in the Secondary Prevention of Small Subcortical Strokes study.

Pablo E Pérgola, Carole L White, John W Graves, Christopher S Coffey, Silvina B Tonarelli, Robert G Hart, Oscar R Benavente, SPS3 Investigators

Abstract readValidation Study
In one paragraph

Article in Blood pressure monitoring, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  7. The Secondary Prevention of Small Subcortical Strokes (SPS3) study.International journal of stroke : official journal of the International Stroke Society · 2011
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  8. Article
  9. Effect of Postural Hypotension on Recurrent Stroke: Secondary Prevention of Small Subcortical Strokes (SPS3) Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2019
    Article
  10. Article
  11. Article
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  14. The Role of Brachial Pulse Pressure as an Indicator of Intracranial Atherosclerosis: The Atahualpa Project.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017
    Article
  15. The Relationship Between High Pulse Pressure and Low Ankle-Brachial Index. Potential Utility in Screening for Peripheral Artery Disease in Population-Based Studies.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pablo E PérgolaDepartment of Medicine, Division of Nephrology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Carole L White
John W Graves
Christopher S Coffey
Silvina B Tonarelli
Robert G Hart
Oscar R Benavente
SPS3 Investigators

Funding

SECONDARY PREVENTION OF SMALL SUBCORTICAL STROKES (SPSS)U01NS038529 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BENAVENTE, OSCAR R · 2003 to 2012
$62.9M
NINDS NIH HHS U01 NS038529
6 · The paper itself

Abstract

rationaleThe Secondary Prevention of Small Subcortical Strokes study is a multicenter, international trial funded by the National Institutes of Health testing the role of lowering systolic blood pressure to <130 mmHg in the prevention of stroke recurrence and cognitive decline in patients with recent symptomatic small subcortical stroke. Reliable and unbiased blood pressure measurement is critical to successful completion of the trial.

methodsWe looked at the reliability and validity of both the device used for blood pressure measurement and observer performance during measurement to assess the quality of blood pressure determination in the study. The Colin 8800C blood pressure device was tested for performance to Association for the Advancement of Medical Instrumentation standards and for presence of skipped digits. Observer performance was tested by examining adherence to the Secondary Prevention of Small Subcortical Strokes protocol.

resultsThe mean difference (in mmHg) between the Colin device and the average of the two observers was 3.9 (SD 6.7) and -2.1 (SD 6.1) for systolic and diastolic pressures respectively, thereby meeting Association for the Advancement of Medical Instrumentation requirements. No skipped digits were found between 82-230 and 40-120 mmHg for systolic and diastolic pressures, respectively. Observer performance was excellent with greater than 90% of patients having blood pressure measured consistently according to the protocol.

conclusionsDevice and observer performance in Secondary Prevention of Small Subcortical Strokes is excellent. Interpretation of the Secondary Prevention of Small Subcortical Strokes data for the effect of lowering systolic blood pressure on patient outcomes will not likely be adversely affected by these factors. Accuracy will be monitored throughout the remainder of the trial to ensure that this high quality is maintained.

Indexed as

Blood PressureAlgorithmsHumansObserver VariationRandomized Controlled Trials as TopicReproducibility of ResultsSphygmomanometersStrokeSystole

Identifiers

PMID17303981
PMCPMC3970705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.