Evidence map›Paper›PMID 17302913›Full record

Trial reportBritish journal of clinical pharmacology2007

Palatability of angiotensin II antagonists among nephropathic children.

Chiara M Meier, Giacomo D Simonetti, Silvia Ghiglia, Emilio Fossali, Patrizia Salice, Costanzo Limoni, Mario G Bianchetti, CHIld Project

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in British journal of clinical pharmacology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Drug therapy in kidney disease.British journal of clinical pharmacology · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chiara M MeierOspedale San Giovanni Bellinzona and Ospedale della Beata Vergine, Mendrisio, Switzerland.
Giacomo D Simonetti
Silvia Ghiglia
Emilio Fossali
Patrizia Salice
Costanzo Limoni
Mario G Bianchetti
CHIld Project

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

what is already known about this subject* Among children, medication palatability is crucial for adherence to therapeutic regimen. * Several studies have measured the palatability of antimicrobial suspensions in paediatric patients by means of a visual analogue scale palatability score. WHAT THIS STUDY ADDS: * This is the first analysis comparing the taste and smell acceptability of angiotensin II receptor blockers among paediatric patients with kidney disease. * From the perspective of the child with kidney disease, the taste of pulverized candesartan is significantly superior to that of pulverized irbesartan, losartan, telmisartan or valsartan.

aimAngiotensin II receptor blockers are widely prescribed in kidney disease. Among children, medication palatability is crucial for adherence.

methodsTaste and smell acceptability of five angiotensin II receptor blockers were compared among 21 nephropathic children using a visual analogue scale palatability score.

resultsThe score assigned to pulverized tablets of candesartan cilexetil was significantly higher than that assigned to pulverized tablets of irbesartan, losartan, telmisartan and valsartan.

conclusionsFrom the perspective of the nephropathic child, the taste of pulverized candesartan cilexetil is superior to that of irbesartan, losartan, telmisartan or valsartan.

Indexed as

Patient SatisfactionAngiotensin II Type 1 Receptor BlockersAntihypertensive AgentsBenzimidazolesBenzoatesBiphenyl CompoundsChildChild, PreschoolFemaleHumansIrbesartanKidney DiseasesLosartanMalePatient ComplianceSmellAngiotensin II Type 1 Receptor BlockersAntihypertensive AgentsBenzimidazolesBenzoatesBiphenyl Compoundscandesartan cilexetilIrbesartanLosartanTelmisartanTetrazolesValineValsartan

Identifiers

PMID17302913
PMCPMC2000746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.