ArticleJournal of clinical microbiology2007
Comparison of the MChip to viral culture, reverse transcription-PCR, and the QuickVue influenza A+B test for rapid diagnosis of influenza.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 72 citations in OpenAlex.
- Article
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- Acoustical Slot Mode Sensor for the Rapid Coronaviruses Detection.Sensors (Basel, Switzerland) · 2021Article
- Clinical Impact of Rapid Point-of-Care PCR Influenza Testing in an Urgent Care Setting: a Single-Center Study.Journal of clinical microbiology · 2019Article
- Should clinical case definitions of influenza in hospitalized older adults include fever?Influenza and other respiratory viruses · 2015Article
- Performance of rapid influenza diagnostic tests (QuickVue) for influenza A and B Infection in India.Indian journal of medical microbiology · 2015Article
- Development and clinical testing of a simple, low-density gel element array for influenza identification, subtyping, and H275Y detection.Journal of virological methods · 2014Article
- Comparative evaluation of effectiveness of IAVchip DNA microarray in influenza A diagnosis.TheScientificWorldJournal · 2014Article
- A cost-effectiveness analysis of "test" versus "treat" patients hospitalized with suspected influenza in Hong Kong.PloS one · 2012Article
- Short report: Rapid-test based identification of influenza as an etiology of acute febrile illness in Cambodia.The American journal of tropical medicine and hygiene · 2011Article
- VereFlu™: an integrated multiplex RT-PCR and microarray assay for rapid detection and identification of human influenza A and B viruses using lab-on-chip technology.Archives of virology · 2011Article
- Diagnosis of influenza from respiratory autopsy tissues: detection of virus by real-time reverse transcription-PCR in 222 cases.The Journal of molecular diagnostics : JMD · 2011Article
- Real-time detection of influenza a, influenza B, and respiratory syncytial virus a and B in respiratory specimens by use of nanoparticle probes.Journal of clinical microbiology · 2010Article
- MChip, a low density microarray, differentiates among seasonal human H1N1, North American swine H1N1, and the 2009 pandemic H1N1.Influenza and other respiratory viruses · 2010Article
- High sensitivity of a rapid immunochromatographic test for detection of influenza A virus 2009 H1N1 in nasopharyngeal aspirates from young children.Journal of clinical microbiology · 2010Article
- Rapid semi-automated quantitative multiplex tandem PCR (MT-PCR) assays for the differential diagnosis of influenza-like illness.BMC infectious diseases · 2010Article
- Human metapneumovirus in hospitalized children in Amman, Jordan.Journal of medical virology · 2010Article
- The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases.Respirology (Carlton, Vic.) · 2010Article
- Burden of respiratory syncytial virus in hospitalized infants and young children in Amman, Jordan.Scandinavian journal of infectious diseases · 2010Article
- Performance of an influenza rapid test in children in a primary healthcare setting in Nicaragua.PloS one · 2009Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
The performance of a diagnostic microarray (the MChip assay) for influenza was compared in a blind study to that of viral culture, reverse transcription (RT)-PCR, and the QuickVue Influenza A+B test. The patient sample data set was composed of 102 respiratory secretion specimens collected between 29 December 2005 and 2 February 2006 at Scott & White Hospital and Clinic in Temple, Texas. Samples were collected from a wide range of age groups by using direct collection, nasal/nasopharyngeal swabs, or nasopharyngeal aspiration. Viral culture and the QuickVue assay were performed at the Texas site at the time of collection. Aliquots for each sample, identified only by study numbers, were provided to the University of Colorado and Vanderbilt University teams for blinded analysis. When referenced to viral culture, the MChip exhibited a clinical sensitivity of 98% and a clinical specificity of 98%. When referenced to RT-PCR, the MChip assay exhibited a clinical sensitivity of 92% and a clinical specificity of 98%. While the MChip assay currently requires 7 to 8 h to complete the analysis, a significant advantage of the test for influenza virus-positive samples is simultaneous detection and full subtype identification for the two subtypes currently circulating in humans (A/H3N2 and A/H1N1) and avian (A/H5N1) viruses.
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