ArticleArchives of disease in childhood2007
Comparison of metabolic syndrome prevalence using eight different definitions: a critical approach.
Article in Archives of disease in childhood, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 197 citations in OpenAlex.
- Exploring the Prevalence and Components of Metabolic Syndrome in Sub-Saharan African Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis.Journal of obesity · 2024Pooled it
- Markers of metabolic syndrome in obese children before and after 1-year lifestyle intervention program.European journal of nutrition · 2011Trial
- Metabolic syndrome, adipokines and ghrelin in overweight and obese schoolchildren: results of a 1-year lifestyle intervention programme.European journal of pediatrics · 2011Trial
- Monitoring metabolic health in the adolescent population of Rarotonga: a multi-year cross-sectional study from 2016 to 2023.BMC public health · 2026Article
- Confirmatory-factor-analysis-derived metabolic syndrome risk score: development, validation, and clinical utility in dual adolescent populations.Pediatric research · 2026Article
- From Altered Metabolic and Anthropometric Parameters to Metabolic Syndrome: A Cross-Sectional Survey on the Effectiveness and Safety of Neo-PolicaptilHealthcare (Basel, Switzerland) · 2025Article
- Unmasking heterogeneity in metabolic syndrome in a national sample of disaggregated Asian American subgroups.Obesity pillars · 2025Article
- ObMetrics: A Shiny app to assist in metabolic syndrome assessment in paediatric obesity.Pediatric obesity · 2025Observational
- Early Endocrine and Metabolic Complications in Childhood Cancer Survivors-Experience from a Tertiary Care Pediatric Oncology Center in South India.South Asian journal of cancer · 2025Article
- Effects of multidisciplinary therapy on energy balance, inflammation, and metabolic diseases in adolescents with obesity: A narrative review.Annals of the New York Academy of Sciences · 2024Review
- Dietary intake, obesity, and metabolic risk factors among children and adolescents in the SEACO-CH20 cross-sectional study.Scientific reports · 2024Article
- The impact of metabolic disorders on management of periodontal health in children.Pediatric discovery · 2024Article
- Not Only Metabolic Complications of Childhood Obesity.Nutrients · 2024Review
- Pulse Wave Analysis in Obese Children with and without Metabolic SyndromeJournal of clinical research in pediatric endocrinology · 2023Article
- The association between urinary cotinine level and metabolic syndrome profiles among adolescents: findings from the Ewha Birth and growth study.BMC public health · 2023Article
- Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity.Children (Basel, Switzerland) · 2023Review
- DNA Methylation Is a Potential Biomarker for Cardiometabolic Health in Mexican Children and Adolescents.Epigenomes · 2023Article
- Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study.Frontiers in endocrinology · 2023Observational
- Impact of risk factors related to metabolic syndrome on acute myocardial infarction in younger patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Review
- Arterial Stiffness Assessment by Pulse Wave Velocity in Patients with Metabolic Syndrome and Its Components: Is It a Useful Tool in Clinical Practice?International journal of environmental research and public health · 2022Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMultiple definitions of the metabolic syndrome (MS) have been proposed for children, adolescents and adults. The aim of this study was to analyse the variations in the MS prevalence using different definitions and to examine which factors influence the frequency of the MS in childhood and adolescence. METHODS AND
designThe prevalence of the MS according to eight proposed definitions was studied in 1205 Caucasian overweight children and adolescents aged 4-16 years (mean body mass index (BMI) 27.3 kg/m2, mean age 11.8 years, 46% males, 39% prepubertal). Blood pressure, waist circumference and fasting triglycerides, HDL-cholesterol, total cholesterol, insulin and glucose concentrations were determined. Overweight was defined according to the International Task Force of Obesity in Childhood. Degree of overweight was calculated as standard deviation score of BMI (SDS-BMI). Insulin resistance was estimated based on the HOMA model.
resultsThe prevalence of the MS varied significantly (p<0.001), being between 6% and 39% depending on the different definitions. Only 2% of the children fulfilled the criteria of the MS in all definitions. Insulin resistance and degree of overweight were associated with the MS. In most definitions, pubertal stage did not influence the occurrence of the MS. In a principal component analysis, total cholesterol, triglycerides and waist circumference showed high final communality estimates.
conclusionsSince the prevalence of the MS varied widely in overweight children and adolescents depending on the proposed definition used, an internationally accepted uniform definition of the MS is necessary to compare different populations and studies.
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