ArticleBritish journal of cancer2007
Small cell oesophageal carcinoma: an institutional experience and review of the literature.
Article in British journal of cancer, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Sequential Esophageal Squamous Cell Carcinoma and Small Cell Carcinoma Following Prior Nissen Fundoplication.Cureus · 2026Article
- A rare case report of esophageal neuroendocrine carcinoma mimicking a submucosal tumor: Diagnosis confirmed by endoscopic ultrasound-guided fine-needle aspiration.The Journal of international medical research · 2025Article
- Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus.Frontiers in bioinformatics · 2025Article
- Treatment strategies for limited-stage small cell carcinoma of the esophagus: evidence from a Chinese multicenter cohort study and the American SEER database.Journal of thoracic disease · 2024Article
- Article
- Platinum-doublet chemotherapy for advanced gastroenteropancreatic neuroendocrine carcinoma: a systematic review and meta-analysis.Discover oncology · 2022Article
- Endoscopic submucosal dissection combined with adjuvant chemotherapy for early-stage neuroendocrine carcinoma of the esophagus: A case report.World journal of clinical cases · 2022Article
- Small cell carcinoma of the oesophagus: experience of an Indian Tertiary Cancer Centre.Ecancermedicalscience · 2022Article
- Distinct mutational backgrounds and clonal architectures implicated prognostic discrepancies in small-cell carcinomas of the esophagus and lung.Cell death & disease · 2021Article
- Primary small cell oesophageal carcinoma: A retrospective study of different treatment modalities.World journal of clinical oncology · 2020Article
- Population-based analysis of small cell carcinoma of the esophagus using the SEER database.Journal of thoracic disease · 2020Article
- A retrospective study of definitive chemoradiotherapy in patients with resectable small cell neuroendocrine carcinoma of the esophagus.Esophagus : official journal of the Japan Esophageal Society · 2020Article
- Systematic analysis of the transcriptome in small-cell carcinoma of the oesophagus reveals its immune microenvironment.Clinical & translational immunology · 2020Article
- A rare case of bipartite combined tumour of the oesophagus.World journal of surgical oncology · 2019Article
- The Role of Surgery in Treating Resectable Limited Disease of Esophageal Neuroendocrine Carcinoma.World journal of surgery · 2018Article
- The genomic landscape of small cell carcinoma of the esophagus.Cell research · 2018Article
- Primary Esophagogastric Neuroendocrine Carcinoma: a Retrospective Study from the Nottingham Upper Gastrointestinal Cancer Center.Journal of gastrointestinal cancer · 2018Article
- Article
- Small Cell Carcinoma of the Esophagus: Clinicopathological Features and Outcome of 22 Cases.Iranian Red Crescent medical journal · 2015Article
- Neuroendocrine Carcinomas of the Gastroenteropancreatic System: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2015Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary small cell oesophageal carcinoma (SCOC) is rare, prognosis is poor and there is no established optimum treatment strategy. It shares many clinicopathologic features with small cell carcinoma of the lung; therefore, a similar staging and treatment strategy was adopted. Sixteen cases referred to Velindre hospital between 1998 and 2005 were identified. Patients received platinum-based combination chemotherapy if appropriate. Those with limited disease (LD) received radical radiotherapy (RT) to all sites of disease on completion of chemotherapy. Median survival of all patients was 13.2 months. Median survival of patients with LD was significantly longer than those with extensive disease (24.4 vs 9.1 months, P=0.034). This is one of the largest single institution series in the world literature. Combined modality therapy using platinum-based combination chemotherapy and radical RT may allow a nonsurgical approach to management, avoiding the morbidity of oesophagectomy. Prophylactic cranial irradiation is controversial, and should be discussed on an individual basis.
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