Evidence map›Paper›PMID 17292372›Full record

ReviewInternational journal for parasitology2007

Electrophysiological studies of malaria parasite-infected erythrocytes: current status.

Henry M Staines, Abdulnaser Alkhalil, Richard J Allen, Hugo R De Jonge, Elvira Derbyshire, Stéphane Egée, Hagai Ginsburg, David A Hill, Stephan M Huber, Kiaran Kirk and 12 more

Open access · bronzeAbstract readReview
In one paragraph

Review in International journal for parasitology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
  2. Article
  3. Microorganisms · 2024
    Article
  4. Review
  5. Unique Properties of Nutrient Channels onPathogens (Basel, Switzerland) · 2023
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. The conserved clag multigene family of malaria parasites: essential roles in host-pathogen interaction.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 7 countries.

Henry M StainesCentre for Infection, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0RE, UK. hstaines@sgul.ac.uk
Abdulnaser Alkhalil
Richard J Allen
Hugo R De Jonge
Elvira Derbyshire
Stéphane Egée
Hagai Ginsburg
David A Hill
Stephan M Huber
Kiaran Kirk
Florian Lang
Godfrey Lisk
Eugene Oteng
Ajay D Pillai
Kempaiah Rayavara
Sherin Rouhani
Kevin J Saliba
Crystal Shen
Tsione Solomon
Serge L Y Thomas
Patrick Verloo
Sanjay A Desai
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USAustralian National University · AUCentre National de la Recherche Scientifique · FRErasmus MC · NLSt George's, University of London · GBUniversity of Tübingen · DEHebrew University of Jerusalem · IL

Funding

The Plasmodial Surface Anion Channel And Malaria Parasite Nutrient AcquisitionZ01AI000882 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI DESAI, SANJAY A · 2001 to 2008
$1.5M
Intramural NIH HHS Z01 AI000882Wellcome Trust 076441
6 · The paper itself

Abstract

The altered permeability characteristics of erythrocytes infected with malaria parasites have been a source of interest for over 30 years. Recent electrophysiological studies have provided strong evidence that these changes reflect transmembrane transport through ion channels in the host erythrocyte plasma membrane. However, conflicting results and differing interpretations of the data have led to confusion in this field. In an effort to unravel these issues, the groups involved recently came together for a week of discussion and experimentation. In this article, the various models for altered transport are reviewed, together with the areas of consensus in the field and those that require a better understanding.

Indexed as

AnimalsAnionsCell Membrane PermeabilityDantroleneErythrocytesFurosemideHumansIon ChannelsMalaria, FalciparumMembrane Transport ModulatorsNitrobenzoatesOxidation-ReductionPatch-Clamp TechniquesPlasmodium falciparum5-nitro-2-(3-phenylpropylamino)benzoic acidAnionsDantroleneFurosemideIon ChannelsMembrane Transport ModulatorsNitrobenzoates

Identifiers

PMID17292372
PMCPMC2746352
OpenAlexW2055792051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.