ReviewPaediatric drugs2007
Management of chronic functional constipation in childhood.
Review in Paediatric drugs, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 33 citations in OpenAlex.
- The effect of pelvic physiotherapy on reduction of functional constipation in children: design of a multicentre randomised controlled trial.BMC pediatrics · 2013Trial
- Exploring Community Perspectives on Functional Paediatric Habitual Constipation.International journal of environmental research and public health · 2024Article
- Review
- Serotonin, ghrelin, and motilin gene/receptor/transporter polymorphisms in childhood functional constipation.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Review
- Paediatrics: how to manage functional constipation.Drugs in context · 2021Review
- Pediatrician's knowledge on the approach of functional constipation.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2016Article
- Management of Functional Constipation in Children: Therapy in Practice.Paediatric drugs · 2015Article
- Constipation in children: novel insight into epidemiology, pathophysiology and management.Journal of neurogastroenterology and motility · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic functional constipation is a common problem in childhood, with soiling a significant issue. The morbidity is high and the treatment is complex. There is a very poor evidence base for the drug treatments used and there are considerable differences in practice in different units. The key to successful management is early diagnosis and prompt treatment with an emphasis on holistic care with multidisciplinary support where needed. For example, the practical approach in our unit at the Southampton General Hospital, Southampton, England emphasizes the non-drug aspects including patient education and behavioral modification and uses stimulant laxatives, usually in a high dose as first-line therapy. There is an urgent need for prospective comparative studies to investigate different treatment regimens and for longitudinal studies to examine the long-term outcome of chronic constipation and the factors that determine it. The lack of a significant evidence base for the use of the most widely used agents proves a significant challenge in the production of evidence-based guidelines and highlights the paucity of data for most of the widely used treatments for childhood constipation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.