ReviewDialogues in clinical neuroscience2006
Angst and the amygdala.
Review in Dialogues in clinical neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study.Translational psychiatry · 2024Article
- Functional changes in neural mechanisms underlying post-traumatic stress disorder in World Trade Center responders.Translational psychiatry · 2023Article
- Mild Hyperhomocysteinemia Causes Anxiety-like Behavior and Brain Hyperactivity in Rodents: Are ATPase and Excitotoxicity by NMDA Receptor Overstimulation Involved in this Effect?Cellular and molecular neurobiology · 2022Article
- Chronic psychosocial stress during pregnancy affects maternal behavior and neuroendocrine function and modulates hypothalamic CRH and nuclear steroid receptor expression.Translational psychiatry · 2020Article
- Emotion Regulation Using Virtual Environments and Real-Time fMRI Neurofeedback.Frontiers in neurology · 2018Article
- Modulation of the Hypothalamic-Pituitary-Adrenal Axis by Early Life Stress Exposure.Frontiers in cellular neuroscience · 2017Review
- Prenatal stress programs neuroendocrine stress responses and affective behaviors in second generation rats in a sex-dependent manner.Psychoneuroendocrinology · 2015Article
- The neurobiological correlates of childhood adversity and implications for treatment.Acta psychiatrica Scandinavica · 2013Review
- Function and innervation of the locus ceruleus in a macaque model of Functional Hypothalamic Amenorrhea.Neurobiology of disease · 2013Article
- Prenatal psychobiological predictors of anxiety risk in preadolescent children.Psychoneuroendocrinology · 2012Article
- Neurobehavioral risk is associated with gestational exposure to stress hormones.Expert review of endocrinology & metabolism · 2012Article
- Chronic, noninvasive glucocorticoid administration suppresses limbic endocannabinoid signaling in mice.Neuroscience · 2012Article
- Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder.Journal of psychiatry & neuroscience : JPN · 2009Review
- Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?Depression and anxiety · 2009Review
- Nesfatin-1 increases anxiety- and fear-related behaviors in the rat.Psychopharmacology · 2008Article
- Effects of gastrin-releasing peptide agonist and antagonist administered to the basolateral nucleus of the amygdala on conditioned fear in the rat.Psychopharmacology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fear is an adaptation to danger, but excessive fear underlies diverse forms of mental anguish and pathology. One neural site linked to a sense of adversity is the amygdala, and one neuropeptide, corticotropin-releasing hormone (CRH), is localized within the central nucleus of the amygdala. Glucocorticoids enhance the production of CRH in this region of the brain, resulting in increased attention to external events and, when sustained for longer periods of time, perhaps contributing to anxious depression.
Indexed as
Identifiers
17290799PMC3181834W135498258What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.