ArticleEMBO reports2007
Upstream promoter sequences and alphaCTD mediate stable DNA wrapping within the RNA polymerase-promoter open complex.
Article in EMBO reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Molecular insights into the fine-tuning of pH-dependent ArsR-mediated regulation of the SabA adhesin in Helicobacter pylori.Nucleic acids research · 2024Article
- Review
- Single-molecule insights into torsion and roadblocks in bacterial transcript elongation.Transcription · 2021Article
- Composition of Transcription Machinery and Its Crosstalk with Nucleoid-Associated Proteins and Global Transcription Factors.Biomolecules · 2021Review
- Metal-responsive promoter DNA compaction by the ferric uptake regulator.Nature communications · 2016Article
- New insights into the regulatory mechanisms of ppGpp and DksA on Escherichia coli RNA polymerase-promoter complex.Nucleic acids research · 2015Article
- Molecular mechanisms of transcription through single-molecule experiments.Chemical reviews · 2014Review
- Single-molecule studies of transcription: from one RNA polymerase at a time to the gene expression profile of a cell.Journal of molecular biology · 2011Article
- Three-dimensional EM structure of an intact activator-dependent transcription initiation complex.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Insights into the architecture and stoichiometry of Escherichia coli PepA*DNA complexes involved in transcriptional control and site-specific DNA recombination by atomic force microscopy.Nucleic acids research · 2009Article
- Sequence-dependent upstream DNA-RNA polymerase interactions in the open complex with lambdaPR and lambdaPRM promoters and implications for the mechanism of promoter interference.Journal of molecular biology · 2009Article
- Activation of transcription initiation by Spx: formation of transcription complex and identification of a Cis-acting element required for transcriptional activation.Molecular microbiology · 2008Article
- Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Transcription initiation by mix and match elements: flexibility for polymerase binding to bacterial promoters.Gene regulation and systems biology · 2007Article
- Mechanisms of physiological regulation of RNA synthesis in bacteria: new discoveries breaking old schemes.Journal of applied genetics · 2007Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
We show that the extent of stable DNA wrapping by Escherichia coli RNA polymerase (RNAP) in the RNAP-promoter open complex depends on the sequence of the promoter and, in particular, on the sequence of the upstream region of the promoter. We further show that the extent of stable DNA wrapping depends on the presence of the RNAP alpha-subunit carboxy-terminal domain and on the presence and length of the RNAP alpha-subunit interdomain linker. Our results indicate that the extensive stable DNA wrapping observed previously in the RNAP-promoter open complex at the lambda P(R) promoter is not a general feature of RNAP-promoter open complexes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.