ArticleRheumatology international2007
Association of bone mineral density and vertebral deformity in patients with rheumatoid arthritis.
Article in Rheumatology international, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Vertebral fractures affect functional status in postmenopausal rheumatoid arthritis patients.Journal of bone and mineral metabolism · 2014Trial
- Prevalence of vertebral fractures in a disease activity steered cohort of patients with early active rheumatoid arthritis.BMC musculoskeletal disorders · 2012Trial
- Impact of immunosuppressive therapy and clinical risk factors on the prevalence of low bone mineral density in rheumatic diseases.Frontiers in medicine · 2026Article
- [Systemic versus local demineralization in rheumatoid arthritis : Insights into the bone].Zeitschrift fur Rheumatologie · 2025Review
- Anti-Inflammatory Effects of Low-Dose Glucocorticoids Compensate for Their Detrimental Effects on Bone Mineral Density in Patients with Rheumatoid Arthritis.Journal of clinical medicine · 2021Article
- Review
- The risk of osteoporotic fractures according to the FRAX model in Korean patients with rheumatoid arthritis.Journal of Korean medical science · 2014Article
- Prevalence and risk factors associated with low-impact fractures in men with rheumatoid arthritis.Clinical rheumatology · 2014Article
- Morphological and volumetric analysis of the development of atlantoaxial vertical subluxation in rheumatoid arthritis.Yonago acta medica · 2013Article
- A review of the use of dual-energy X-ray absorptiometry (DXA) in rheumatology.Open access rheumatology : research and reviews · 2012Review
- Perforation rates of cervical pedicle screw insertion by disease and vertebral level.The open orthopaedics journal · 2010Article
- Skeletal health among African Americans with recent-onset rheumatoid arthritis.Arthritis and rheumatism · 2009Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the association of vertebral deformities developed as a result of osteoporosis in female patients with rheumatoid arthritis (RA) with bone mineral density (BMD) and disease activity parameters. In the study, 100 female patients with the diagnosis of RA and 56 healthy subjects were recruited. Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and rheumatoid factor (RF) tests were performed and the number of swollen and tender joints, level of pain and health assessment questionnaire (HAQ) were recorded in order to evaluate disease activity. Anteroposterior and lateral thoracic and lumbosacral roentgenograms of all patients were taken for radiological examination and deformities of vertebrae were assessed. BMD measurements of patients were performed on vertebrae L1-4 of lumbar region and on total hip, femur neck, trochanter and Ward's triangle of the right side. Vertebral deformity was established in 30% of RA patient group and 7.1% of control group and this was statistically significant. In the statistical analysis, no statistically significant difference was found between BMD measurements of RA and control groups. Patients with RA were divided into two subgroups with regard to using corticosteroids (CS) or not. Vertebral deformity was 32.4% in the subgroup using CS and 24.1% in the subgroup not using CS, and the difference was not statistically significant. There was a correlation between number of deformed joint and age and vertebral deformity incidence. RA is a risk factor on its own for the development of osteoporosis and vertebral deformity and this risk increases by age, excess number of deformed joints and severe course of disease. We think that precautions should be taken immediately to suppress the disease activity as well as to protect the quality and density of bone and to prevent the development of vertebral deformity and fracture while planning the treatment of patients with RA.
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