ReviewPflugers Archiv : European journal of physiology2007
Is the vascular endothelium under the control of aldosterone? Facts and hypothesis.
Review in Pflugers Archiv : European journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- Salt sensitivity and hypertension.Journal of human hypertension · 2021Review
- Dietary salt regulates epithelial sodium channels in rat endothelial cells: adaptation of vasculature to salt.British journal of pharmacology · 2015Article
- Elasticity changes anti-correlate with NO production for human endothelial cells stimulated with TNF-α.Pflugers Archiv : European journal of physiology · 2012Article
- Nitric oxide release follows endothelial nanomechanics and not vice versa.Pflugers Archiv : European journal of physiology · 2010Article
- Aldosterone receptor sites on plasma membrane of human vascular endothelium detected by a mechanical nanosensor.Pflugers Archiv : European journal of physiology · 2009Article
- Effect of excessive salt intake: role of plasma sodium.Current hypertension reports · 2009Review
- Elasticity measurement of living cells with an atomic force microscope: data acquisition and processing.Pflugers Archiv : European journal of physiology · 2008Article
- How steroid hormones act on the endothelium--insights by atomic force microscopy.Pflugers Archiv : European journal of physiology · 2008Review
- Nano-surgery at the leukocyte-endothelial docking site.Pflugers Archiv : European journal of physiology · 2008Article
- Probing cellular microenvironments and tissue remodeling by atomic force microscopy.Pflugers Archiv : European journal of physiology · 2008Review
- Imaging CFTR in its native environment.Pflugers Archiv : European journal of physiology · 2008Review
- Aldosterone and amiloride alter ENaC abundance in vascular endothelium.Pflugers Archiv : European journal of physiology · 2008Article
- Plasma sodium stiffens vascular endothelium and reduces nitric oxide release.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluid and electrolyte balance in the human organism is controlled by aldosterone, a mineralocorticoid hormone of the suprarenal glands. The major target cells are localized in the kidney where the hormone controls transepithelial salt transport. Over the past few years, evidence has been accumulated that cells of the cardiovascular system are also targeted by the hormone. As an example, endothelial cells resemble similar mechanisms triggered by aldosterone as shown for the kidney. Although the pathological alterations induced by aldosterone excess are obvious, the physiological changes are largely unknown. On the basis of recent experiments, using atomic force microscopy as an imaging tool and a mechanical sensor, I present a hypothesis on the physiological role of aldosterone in endothelial function and its potential implications in the control of blood pressure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.