ArticleDigestive diseases and sciences1992
Survival of Lactobacillus species (strain GG) in human gastrointestinal tract.
Article in Digestive diseases and sciences, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 3 syntheses or guidelines pooled it, 554 citations in OpenAlex.
- Pooled it
- Evidence-based guidelines for use of probiotics in preterm neonates.BMC medicine · 2011Pooled it
- Efficacy of probiotic use in acute diarrhea in children: a meta-analysis.Digestive diseases and sciences · 2002Pooled it
- Investigation of the Efficacy of Lactobacillus rhamnosus GG in Infants With Cow's Milk Protein Allergy: a Randomised Double-Blind Placebo-Controlled Trial.Probiotics and antimicrobial proteins · 2020Trial
- Effect of Lactobacillus rhamnosus GG Administration on Vancomycin-Resistant Enterococcus Colonization in Adults with Comorbidities.Antimicrobial agents and chemotherapy · 2015Trial
- Trial
- In vitro and in vivo survival and colonic adhesion of Pediococcus acidilactici MTCC5101 in human gut.BioMed research international · 2013Trial
- Effect of probiotic Lactobacillus (Lacidofil® cap) for the prevention of antibiotic-associated diarrhea: a prospective, randomized, double-blind, multicenter study.Journal of Korean medical science · 2010Trial
- Survival of Lactobacillus reuteri DSM 17938 and Lactobacillus rhamnosus GG in the human gastrointestinal tract with daily consumption of a low-fat probiotic spread.Applied and environmental microbiology · 2009Trial
- Prevention of antibiotic-associated diarrhoea by a fermented probiotic milk drink.European journal of clinical nutrition · 2008Trial
- Survival of Lactobacillus casei in the human digestive tract after consumption of fermented milk.Applied and environmental microbiology · 2006Trial
- Trial
- Trial
- Screening of probiotic activities of forty-seven strains of Lactobacillus spp. by in vitro techniques and evaluation of the colonization ability of five selected strains in humans.Applied and environmental microbiology · 1999Trial
- Management of acute diarrhoea with low osmolarity oral rehydration solutions and Lactobacillus strain GG.Archives of disease in childhood · 1998Trial
- Oral bacteriotherapy for viral gastroenteritis.Digestive diseases and sciences · 1994Trial
- Enteral feeding of premature infants with Lactobacillus GG.Archives of disease in childhood · 1993Trial
- A non-dairy probiotic's (poi) influence on changing the gastrointestinal tract's microflora environment.Alternative therapies in health and medicineTrial
- Lactobacillus GG does not affect D-lactic acidosis in diarrheic calves, in a clinical setting.Journal of veterinary internal medicineTrial
- Production of Gamma-Aminobutyric Acid by Levilactobacillus brevis AK19B: Strain Characterization and Process Optimization Using Box-Behnken Design.Probiotics and antimicrobial proteins · 2026Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A newly isolated strain of a species of Lactobacillus of human origin, designated GG (Lactobacillus GG), has been studied to determine its ability to survive in the human gastrointestinal tract. When fed to 76 volunteers as a frozen concentrate or as a fermented preparation in milk or whey, Lactobacillus GG was recovered in the feces of all subjects receiving the fermented milk or whey and in 86% receiving the frozen concentrate when a single fecal specimen was cultured. The organism was also present in the feces of subjects concurrently receiving ampicillin. After terminating feeding of the organism, Lactobacillus GG persisted in the feces of 87% of volunteers four days later and in 33% of subjects seven days later. Lactobacillus GG lowered fecal bacterial beta-glucuronidase activity by approximately 80% in volunteers given the organism for four weeks. These studies demonstrate that Lactobacillus GG can survive and temporarily colonize the human gastrointestinal tract and can affect the metabolic activity of the resident microflora.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.