Evidence map›Paper›PMID 17284678›Full record

ArticleGenome research2007

Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.

King-Hwa Ling, Marie-Adele Rajandream, Pierre Rivailler, Alasdair Ivens, Soon-Joo Yap, Alda M B N Madeira, Karen Mungall, Karen Billington, Wai-Yan Yee, Alan T Bankier and 23 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Genome research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Eimeria proteins: order amidst disorder.Parasites & vectors · 2022
    Review
  5. The complete genome sequence ofWellcome open research · 2021
    Article
  6. ExploringGenes · 2020
    Review
  7. ApiAP2 Transcription Factors in Apicomplexan Parasites.Pathogens (Basel, Switzerland) · 2019
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 8 institutions in 5 countries.

King-Hwa LingMalaysia Genome Institute, UKM-MTDC Smart Technology Centre, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor DE, Malaysia.
Marie-Adele Rajandream
Pierre Rivailler
Alasdair Ivens
Soon-Joo Yap
Alda M B N Madeira
Karen Mungall
Karen Billington
Wai-Yan Yee
Alan T Bankier
Fionnadh Carroll
Alan M Durham
Nicholas Peters
Shu-San Loo
Mohd Noor Mat Isa
Jeniffer Novaes
Michael Quail
Rozita Rosli
Mariana Nor Shamsudin
Tiago J P Sobreira
Adrian R Tivey
Siew-Fun Wai
Sarah White
Xikun Wu
Arnaud Kerhornou
Damer Blake
Rahmah Mohamed
Martin Shirley
Arthur Gruber
Matthew Berriman
Fiona Tomley
Paul H Dear
Kiew-Lian Wan
Newbury College · USWellcome Sanger Institute · GBMalaysia Genome Institute · MYNational University of Malaysia · MYUniversidade de São Paulo · BRInstituto do Sono · BRMRC Laboratory of Molecular Biology · GBUniversiti Putra Malaysia · MY

Funding

Biotechnology and Biological Sciences Research Council S19705Medical Research Council MC_U105131672Wellcome Trust
6 · The paper itself

Abstract

Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis. Eimeria falls in the same phylum (Apicomplexa) as several human and animal parasites such as Cryptosporidium, Toxoplasma, and the malaria parasite, Plasmodium. Here we report the sequencing and analysis of the first chromosome of E. tenella, a chromosome believed to carry loci associated with drug resistance and known to differ between virulent and attenuated strains of the parasite. The chromosome--which appears to be representative of the genome--is gene-dense and rich in simple-sequence repeats, many of which appear to give rise to repetitive amino acid tracts in the predicted proteins. Most striking is the segmentation of the chromosome into repeat-rich regions peppered with transposon-like elements and telomere-like repeats, alternating with repeat-free regions. Predicted genes differ in character between the two types of segment, and the repeat-rich regions appear to be associated with strain-to-strain variation.

Indexed as

AnimalsBase SequenceChromosome MappingChromosome StructuresComputational BiologyEimeria tenellaGenes, ProtozoanMinisatellite RepeatsMolecular Sequence DataPolymorphism, Restriction Fragment LengthSequence Analysis, DNA

Identifiers

PMID17284678
PMCPMC1800922
OpenAlexW2117089128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.