ReviewDrugs2007
Treatment approaches for painful bladder syndrome/interstitial cystitis.
Review in Drugs, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Treatment of bladder pain syndrome and interstitial cystitis: a systematic review.International urogynecology journal · 2016Pooled it
- Clinical Management of Chronic Pelvic Pain in Endometriosis Unresponsive to Conventional Therapy.Journal of personalized medicine · 2022Article
- Sympathetic afferents in the hypogastric nerve facilitate nociceptive bladder activity in cats.American journal of physiology. Renal physiology · 2019Article
- Risk for Irritable Bowel Syndrome in Fibromyalgia Patients: A National Database Study.Medicine · 2017Observational
- Risk for irritable bowel syndrome in fibromyalgia patients: a national database study.Medicine · 2015Article
- LL-37 induced cystitis and the receptor for advanced glycation end-products (RAGE) pathway.Advances in bioscience and biotechnology (Print) · 2013Article
- Effects of combination treatment of intravesical resiniferatoxin instillation and hydrodistention in patients with refractory painful bladder syndrome/interstitial cystitis: a pilot study.International neurourology journal · 2012Article
- A murine model of inflammatory bladder disease: cathelicidin peptide induced bladder inflammation and treatment with sulfated polysaccharides.The Journal of urology · 2011Article
- Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress.Gastroenterology · 2009Article
- Article
- Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications.Human reproduction updateReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Painful bladder syndrome/interstitial cystitis (PBS/IC) is a disease of unknown aetiology, characterised by severe pressure and pain in the bladder area or lower pelvis that is frequently or typically relieved by voiding, along with urgency or frequency of urination in the absence of urinary tract infections. PBS/IC occurs primarily in women, is increasingly recognised in young adults, and may affect as many as 0.1-1% of adult women. PBS/IC is often comorbid with allergies, endometriosis, fibromyalgia, irritable bowel syndrome and panic syndrome, all of which are worsened by stress. As a result, patients may visit as many as five physicians, including family practitioners, internists, gynaecologists, urologists and pain specialists, leading to confusion and frustration. There is no curative treatment; intravesical dimethyl sulfoxide, as well as oral amitriptyline, pentosan polysulfate and hydroxyzine have variable results, with success more likely when these drugs are given together. Pilot clinical trials suggest that the flavonoid quercetin may be helpful. Lack of early diagnosis and treatment can affect outcomes and leads to the development of hyperalgesia/allodynia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.