ArticleAntimicrobial agents and chemotherapy2007
Fluoroquinolone resistance in Haemophilus influenzae is associated with hypermutability.
Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Impact of the COVID-19 pandemic on Haemophilus influenzae infections in pediatric patients hospitalized with community acquired pneumonia.Scientific reports · 2024Article
- Antimicrobial resistance among Haemophilus influenzae isolates responsible for lower respiratory tract infections in Poland, 2005-2019.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Article
- Article
- Molecular characterization of fluoroquinolone resistance in nontypeable Haemophilus influenzae clinical isolates.Antimicrobial agents and chemotherapy · 2015Article
- Levofloxacin-resistant haemophilus influenzae, Taiwan, 2004-2010.Emerging infectious diseases · 2014Article
- Reduced levofloxacin susceptibility in clinical respiratory isolates of Haemophilus influenzae is not yet associated with mutations in the DNA gyrase and topoisomerase II genes in Korea.Yonsei medical journal · 2011Article
- Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone resistance-determining regions.Antimicrobial agents and chemotherapy · 2009Article
- Review
- Melting curve analysis for rapid detection of topoisomerase gene mutations in Haemophilus influenzae.Journal of clinical microbiology · 2009Article
- [Microbiological diagnosis of bronchopulmonary colonization-infection in cystic fibrosis].Enfermedades infecciosas y microbiologia clinica · 2009Review
- Emergence of fluoroquinolone-resistant Haemophilus influenzae strains among elderly patients but not among children.Journal of clinical microbiology · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Forty-three percent (12/28) of ciprofloxacin (CIP)-nonsusceptible respiratory isolates of Haemophilus influenzae were hypermutable, compared with 8.5% (3/35) in the CIP-susceptible control group (P=0.002). CIP-nonsusceptible mutants were obtained with hypermutable strains only; these mutants developed three resistance mechanisms in a step-by-step process: target modifications, loss of a porin protein, and increased efflux.
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Registered trials
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