ArticleInfection and immunity2007
The rag locus of Porphyromonas gingivalis contributes to virulence in a murine model of soft tissue destruction.
Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Virulence diversity amongJournal of oral microbiology · 2026Review
- Exploring the Genetic and Functional Diversity ofInternational journal of molecular sciences · 2025Article
- TheFrontiers in cellular and infection microbiology · 2025Article
- Tobacco-enhanced biofilm formation by Porphyromonas gingivalis and other oral microbes.Molecular oral microbiology · 2024Review
- Prevalence and Phylogenetic Analysis of Lipoprotein-GeneAntibiotics (Basel, Switzerland) · 2023Article
- Modulatory Mechanisms of Pathogenicity inMicroorganisms · 2022Review
- The RagA and RagB proteins of Porphyromonas gingivalis.Molecular oral microbiology · 2021Review
- Composition and Seasonality of Membrane Transporters in Marine Picoplankton.Frontiers in microbiology · 2021Article
- Porphyromonas gingivalis RagB is a proinflammatory signal transducer and activator of transcription 4 agonist.Molecular oral microbiology · 2015Article
- Prevalence of Porphyromonas gingivalis four rag locus genotypes in patients of orthodontic gingivitis and periodontitis.PloS one · 2013Article
- Article
- Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease.PloS one · 2012Article
- Genomic comparison of invasive and rare non-invasive strains reveals Porphyromonas gingivalis genetic polymorphisms.Journal of oral microbiology · 2011Article
- Porphyromonas gingivalis-host interactions in a Drosophila melanogaster model.Infection and immunity · 2011Article
- The core genome of the anaerobic oral pathogenic bacterium Porphyromonas gingivalis.BMC microbiology · 2010Article
- The rag locus of Porphyromonas gingivalis might arise from Bacteroides via horizontal gene transfer.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2010Article
- Tobacco-induced alterations to Porphyromonas gingivalis-host interactions.Environmental microbiology · 2009Article
- Study ofMedical journal of the Islamic Republic of IranArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rag locus of Porphyromonas gingivalis encodes a putative TonB-dependent outer membrane receptor, RagA, and a 55-kDa immunodominant antigen, RagB. Inactivation of either ragA or ragB prevented expression of both RagA and RagB. Both the ragA and ragB mutants were significantly less virulent than wild-type strains in a murine model of infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.