ArticleLangmuir : the ACS journal of surfaces and colloids2007
Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: criteria to identify the third liquid and validation with protein crystallization.
Article in Langmuir : the ACS journal of surfaces and colloids, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Simple and Precise Counting of Viable Bacteria by Resazurin-Amplified Picoarray Detection.Analytical chemistry · 2018Article
- A microfluidics platform for combinatorial drug screening on cancer biopsies.Nature communications · 2018Article
- Biocompatibility of fluids for multiphase drops-in-drops microfluidics.Biomedical microdevices · 2016Article
- Hydrogel-droplet microfluidic platform for high-resolution imaging and sorting of early larval Caenorhabditis elegans.Lab on a chip · 2015Article
- Controlled multistep synthesis in a three-phase droplet reactor.Nature communications · 2014Article
- Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions.Biomicrofluidics · 2013Article
- Evolution of catalysts directed by genetic algorithms in a plug-based microfluidic device tested with oxidation of methane by oxygen.Journal of the American Chemical Society · 2010Article
- High-molecular-weight polymers for protein crystallization: poly-gamma-glutamic acid-based precipitants.Acta crystallographica. Section D, Biological crystallography · 2008Article
- ABO, D blood typing and subtyping using plug-based microfluidics.Analytical chemistry · 2008Article
- Floating electrode optoelectronic tweezers: Light-driven dielectrophoretic droplet manipulation in electrically insulating oil medium.Applied physics letters · 2008Article
- Spontaneous processes and stable structures in some three-phase cellular fluids.The European physical journal. E, Soft matter · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This manuscript describes the effect of interfacial tensions on three-phase liquid-liquid-liquid flow in microfluidic channels and the use of this flow to prevent microfluidic plugs from coalescing. One problem in using microfluidic plugs as microreactors is the coalescence of adjacent plugs caused by the relative motion of plugs during flow. Here, coalescence of reagent plugs was eliminated by using plugs of a third immiscible liquid as spacers to separate adjacent reagent plugs. This work tested the requirements of interfacial tensions for plugs of a third liquid to be effective spacers. Two candidates satisfying the requirements were identified, and one of these liquids was used in the crystallization of protein human Tdp1 to demonstrate its compatibility with protein crystallization in plugs. This method for identifying immiscible liquids for use as a spacer will also be useful for applications involving manipulation of large arrays of droplets in microfluidic channels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.