Evidence map›Paper›PMID 17279333›Full record

ArticleJournal of fluorescence2007

Fluorescence analysis with quantum dot probes for hepatoma under one- and two-photon excitation.

Xuefeng Yu, Liangdong Chen, Yuliang Deng, Kaiyang Li, Ququan Wang, Yan Li, Si Xiao, Li Zhou, Xuan Luo, Jia Liu and 1 more

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Nanoparticles for Improving Cancer Diagnosis.Materials science & engineering. R, Reports : a review journal · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xuefeng YuKey Laboratory of Acoustic and Photonic Materials and Devices of Ministry of Education & Department of Physics, Wuhan University, Wuhan 430072, China.
Liangdong Chen
Yuliang Deng
Kaiyang Li
Ququan Wang
Yan Li
Si Xiao
Li Zhou
Xuan Luo
Jia Liu
Daiwen Pang
Wuhan University · CNZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new class of fluorescent probe produced by conjugating semiconductor quantum dots (QDs) with protein molecule is proposed as an alternative to conventional organic labels. However the fluorescence characteristics of the QD bioconjugates are not clear while they are excitied with one- or two-photon laser pulse. We synthesized specific immunofluorescent probes by linking QDs to alpha fetoprotein (AFP) antibody for specific binding alpha-fetoprotein -an important marker for hepatocellular carcinoma cell lines, and archived specific fluorescence detection with the QDs-Anti-AFP in nude mice. Then, we have analyzed the fluorescence characteristics of QDs-Anti-AFP and original QDs both under one- and two-photon excitations. The results demonstrated that QDs-Anti-AFP's fluorescent spectral and lifetime haven't varied much from that of original QDs. Moreover, QDs-Anti-AFP have exhibited higher fluorescence efficiency than QDs under two-photon examination.

Indexed as

Quantum Dotsalpha-FetoproteinsAnimalsCarcinoma, HepatocellularFluorescenceFluorescent Antibody TechniqueFluorescent DyesHumansLiver NeoplasmsMiceMice, NudePhotonsalpha-FetoproteinsFluorescent Dyes

Identifiers

PMID17279333
OpenAlexW2166396821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.