ArticleJournal of materials science. Materials in medicine2007
Stereological analysis of the poly-(DL-lactide-co-glycolide) submicron sphere prepared by solvent/non-solvent chemical methods and centrifugal processing.
Article in Journal of materials science. Materials in medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Chitosan nanobeads loaded with Biginelli hybrids as cell-selective toxicity systems with a homogeneous distribution of the cell cycle in cancer treatment.RSC advances · 2020Article
- Chitosan Oligosaccharide Lactate Coated Hydroxyapatite Nanoparticles as a Vehicle for the Delivery of Steroid Drugs and the Targeting of Breast Cancer Cells.Journal of materials chemistry. B · 2018Article
- Preparation and characterization of poly(D,L-lactide-co-glycolide) nanoparticles containing ascorbic acid.Journal of biomedicine & biotechnology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fine particles made of poly(lactide-co-glycolide) (DLPLG) are excellent candidates for controlled release of delivering drugs and genes, because of their degradable nature. The preparation of DLPLG submicron spheres poses serious challenges that are not necessarily present when preparing macroparticles. In the present paper, DLPLG powder is produced with chemical method using solvent/non-solvent systems with subsequent centrifugation of the solution. The samples were characterized by infrared spectroscopy (IR), scanning electron microscopy (SEM) and stereological analysis. By changing the aging time with non-solvent and time and velocity of the centrifugal processing, it is possible to influence on the morphology and uniformity of the copolymer particles. Powder of the series with short aging time with non-solvent and longest time and velocity of the centrifugal processing has smallest particles and highest uniformity, where mean particles sizes were between 150 nm and 230 nm depending on which stereological parameters are considered (D(max), maximal diameters, feret X or feret Y).
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.