Evidence map›Paper›PMID 17277925›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2007

Critical weight loss in head and neck cancer--prevalence and risk factors at diagnosis: an explorative study.

Harriët Jager-Wittenaar, Pieter U Dijkstra, Arjan Vissink, Bernard F A M van der Laan, Rob P van Oort, Jan L N Roodenburg

Abstract read
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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Malnutrition and radiation therapy in head and neck cancers, a systematic review on reported definitions and associated factors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  8. Factors associated with weight loss during radiotherapy in patients with stage I or II head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2012
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  15. Demographic, lifestyle, and clinical factors associated with muscle function in patients with head and neck cancer: a prospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  20. Physical activity promotion and participation for people living with and beyond head and neck cancer: A mixed methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Harriët Jager-WittenaarDepartment of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, P.O. Box 30001, 9700 RB, Groningen, The Netherlands. h.jager@fd.umcg.nl
Pieter U Dijkstra
Arjan Vissink
Bernard F A M van der Laan
Rob P van Oort
Jan L N Roodenburg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

goals of workCritical weight loss (> or =5% in 1 month or > or =10% in 6 months) is a common phenomenon in head and neck cancer patients. It is unknown which complaints are most strongly related to critical weight loss in head and neck cancer patients at the time of diagnosis. The aim of this explorative study was to assess the prevalence of critical weight loss and to analyze risk factors for critical weight loss in head and neck cancer patients before treatment. MATERIALS AND

methodsCritical weight loss and factors reducing dietary intake were assessed in 447 patients referred to an ear, nose and throat clinic at the time of diagnosis. MAIN

resultsIn total, data of 407 patients were analyzed. Critical weight loss was present in 19% of the patients. Patients with cancer in the hypopharynx, oropharynx/oral cavity and supraglottic larynx had the highest risk for critical weight loss. Loss of appetite, dysphagia/passage difficulties and loss of taste/aversion were significantly (p < 0.05) associated with critical weight loss.

conclusionsAlready before treatment, critical weight loss is a considerable problem in head and neck cancer patients. Critical weight loss is frequently observed in patients with cancer in the hypopharynx, oropharynx/oral cavity and supraglottic larynx.

Indexed as

Weight LossAgedFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedNutrition DisordersPrevalenceRisk Factors

Identifiers

PMID17277925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.