ArticleAnnals of Saudi medicine
Human papilloma virus-16/18 cervical infection among women attending a family medical clinic in Riyadh.
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence and genotypes' distribution of human papillomavirus among women in Saudi Arabia: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Barriers associated with the parental acceptance of human papillomavirus (HPV) vaccination of minors in Asir, Saudi Arabia: A cross-sectional study.Human vaccines & immunotherapeutics · 2025Article
- Epidemiology of Human Papillomavirus in Saudi Arabia: A Scoping Review of Prevalence, Genotypes, and Risk Factors.Journal of epidemiology and global health · 2025Article
- Human papillomavirus genotypes in Jeddah, Saudi Arabia: prevalence and public health implications.Infectious agents and cancer · 2025Article
- Study of the Prevalence of Human Papillomavirus Genotypes in Jeddah, Saudi Arabia.Journal of epidemiology and global health · 2025Article
- Review
- HPV Vaccine Knowledge and Hesitancy Among Health Colleges' Students at a Saudi University.Journal of multidisciplinary healthcare · 2023Article
- Primary Healthcare in Saudi Arabia: An Evaluation of Emergent Health Trends.Global journal on quality and safety in healthcare · 2021Article
- Knowledge, Attitudes and Practices of Women in the Southern Region of Saudi Arabia Regarding Cervical Cancer and the Pap Smear TestAsian Pacific journal of cancer prevention : APJCP · 2019Article
- Article
- Human papilloma virus early proteins E6 (HPV16/18-E6) and the cell cycle marker P16 (INK4a) are useful prognostic markers in uterine cervical carcinomas in Qassim Region--Saudi Arabia.Pathology oncology research : POR · 2015Article
- Human papillomavirus prevalence and type distribution among women attending routine gynecological examinations in Saudi Arabia.BMC infectious diseases · 2014Observational
- HPV Infection in Cervical and Other Cancers in Saudi Arabia: Implication for Prevention and Vaccination.Frontiers in oncology · 2014Review
- HPV prevalence and genetic predisposition to cervical cancer in Saudi Arabia.Infectious agents and cancer · 2013Article
- Attitudes and perceptions towards HPV vaccination among young women in Saudi Arabia.Journal of family & community medicineArticle
- Prevalence of high-risk human papillomavirus infections in healthy Saudi women attending gynecologic clinics in the western region of Saudi Arabia.Annals of Saudi medicineArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevalence information is lacking on human papillomavirus types 16 and 18 (HPV-16/18) infection in cervical tissues of women residing in Riyadh, Saudi Arabia. In addition, there are no observations on progression to cervical intraepithelial neoplasia (CIN). SUBJECTS AND
methodsPap smear and HPV-16/18 DNA detection by PCR followed by Southern blotting was performed on 120 subjects (Saudi and other Arab nationals) during routine gynecological examination. Some HPV-positive subjects were followed for 4 years, by Pap smear every 6 months and by HPV DNA detection at the end of 4 years.
resultsOverall HPV-16/18 prevalence was 31.6%. HPV-16 prevalence alone was 13.3%, HPV-16 as a mixed infection with HPV-18 was 15%, and all HPV-16 was 28.3%. HPV-18 alone was 3.3%, HPV-18 as a mixed infection with HPV-16 was 15%, and all HPV-18 was 18.3%. Ten subjects had cervical abnormalities with the Pap smear test, six of whom were HPV-16/18 positive, 1 with HPV-16, 1 with HPV-18, and 4 with a mixed infection of HPV-16/18. Of all 23 HPV-16/18-positive subjects, either as individual or mixed infection, followed for 4 years, 7 showed abnormal cytology, 6 at initial examination and 1 during follow-up. Of these 7, 6 reverted to normal without treatment and 1 was treated and became normal after 3 years. None of the subjects progressed to CIN-III.
conclusionA high prevalence of HPV-16/18 was found, but with a low rate of progression to CIN. A significant association with abnormal cytology was found only in patients with HPV-16/18 mixed infection.
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