ArticleThe Plant cell2007
Lack of respiratory chain complex I impairs alternative oxidase engagement and modulates redox signaling during elicitor-induced cell death in tobacco.
Article in The Plant cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 130 citations in OpenAlex.
- Mitochondrial-Nuclear Interactions, Co-Transcription, and Adaptive Evolution in Cytoplasmic Male Sterility.Plant, cell & environment · 2026Review
- Cytochrome c oxidase inactivation in Physcomitrium patens reveals that respiration coordinates plant metabolism.The Plant cell · 2025Article
- Exacerbation of drought-induced physiological and biochemical changes in leaves ofJournal of biosciences · 2024Article
- Contrasting Metabolisms in Green and White Leaf Sectors of VariegatedInternational journal of molecular sciences · 2023Article
- Ascorbate synthesis as an alternative electron source for mitochondrial respiration: Possible implications for the plant performance.Frontiers in plant science · 2022Review
- Inactivation of mitochondrial complex I stimulates chloroplast ATPase in Physcomitrium patens.Plant physiology · 2021Article
- Knockdown ofInternational journal of molecular sciences · 2021Article
- CytochromePlants (Basel, Switzerland) · 2021Article
- The Fungal Effector Avr-Pita Suppresses Innate Immunity by Increasing COX Activity in Rice Mitochondria.Rice (New York, N.Y.) · 2021Article
- Comparison of the response of alternative oxidase and uncoupling proteins to bacterial elicitor induced oxidative burst.PloS one · 2019Article
- Nitrogen Source Dependent Changes in Central Sugar Metabolism Maintain Cell Wall Assembly in Mitochondrial Complex I-DefectiveInternational journal of molecular sciences · 2018Article
- The PPR protein SLOW GROWTH 4 is involved in editing of nad4 and affects the splicing of nad2 intron 1.Plant molecular biology · 2017Article
- Photoperiod Affects the Phenotype of Mitochondrial Complex I Mutants.Plant physiology · 2017Article
- Convergent Evolution of Pathogen Effectors toward Reactive Oxygen Species Signaling Networks in Plants.Frontiers in plant science · 2017Review
- Impaired Cyclic Electron Flow around Photosystem I Disturbs High-Light Respiratory Metabolism.Plant physiology · 2016Article
- NAD Acts as an Integral Regulator of Multiple Defense Layers.Plant physiology · 2016Article
- The Roles of Mitochondrial Reactive Oxygen Species in Cellular Signaling and Stress Response in Plants.Plant physiology · 2016Review
- Disruption of the CYTOCHROME C OXIDASE DEFICIENT1 gene leads to cytochrome c oxidase depletion and reorchestrated respiratory metabolism in Arabidopsis.Plant physiology · 2014Article
- Metabolic control of redox and redox control of metabolism in plants.Antioxidants & redox signaling · 2014Review
- NtERF32: a non-NIC2 locus AP2/ERF transcription factor required in jasmonate-inducible nicotine biosynthesis in tobacco.Plant molecular biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alternative oxidase (AOX) functions in stress resistance by preventing accumulation of reactive oxygen species (ROS), but little is known about in vivo partitioning of electron flow between AOX and the cytochrome pathway. We investigated the relationships between AOX expression and in vivo activity in Nicotiana sylvestris and the complex I-deficient CMSII mutant in response to a cell death elicitor. While a specific AOX1 isoform in the active reduced state was constitutively overexpressed in CMSII, partitioning through the alternative pathway was similar to the wild type. Lack of correlation between AOX content and activity indicates severe metabolic constraints in nonstressed mutant leaves. The bacterial elicitor harpin N(Ea) induced similar timing and extent of cell death and a twofold respiratory burst in both genotypes with little change in AOX amounts. However, partitioning to AOX was increased twofold in the wild type but remained unchanged in CMSII. Oxidative phosphorylation modeling indicated a twofold ATP increase in both genotypes. By contrast, mitochondrial superoxide dismutase activity and reduced forms of ascorbate and glutathione were higher in CMSII than in the wild type. These results demonstrate genetically programmed flexibility of plant respiratory routes and antioxidants in response to elicitors and suggest that sustained ATP production, rather than AOX activity by itself or mitochondrial ROS, might be important for in planta cell death.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.