Evidence map›Paper›PMID 17276332›Full record

ArticleDevelopmental cell2007

Micromanaging alternative splicing during muscle differentiation.

Christopher S Bland, Thomas A Cooper

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Genes of the cGMP-PKG-CaBiochimica et biophysica acta. Molecular basis of disease · 2020
    Article
  2. Article
  3. Article
  4. Article
  5. MicroRNAs (miRNAs) in neurodegenerative diseases.Brain pathology (Zurich, Switzerland) · 2008
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher S BlandDepartment of Pathology, Baylor College of Medicine, Houston, TX 77030, USA.
Thomas A Cooper
Baylor College of Medicine · US

Funding

Initiative for Maximizing Student Development (IMSD) ProgramR25GM056929 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PEREIRA, FRED A · 1998 to 2023
$12.4M
MOLECULAR PATHOGENESIS OF MYOTONIC DYSTROPHYR01AR045653 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI COOPER, THOMAS A · 1999 to 2018
$8.3M
TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM008231 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN · 1990 to 2019
$7.2M
TROPONIN T ALTERNATIVE SPLICING IN EMBRYONIC HEARTR01HL045565 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI COOPER, THOMAS A · 1996 to 2018
$5.5M
NIGMS NIH HHS R25 GM056929NIGMS NIH HHS T32 GM008231
6 · The paper itself

Abstract

A recent report in Genes & Development by Boutz et al. (2007) demonstrates that muscle specific microRNAs (miRNAs) downregulate the alternative splicing regulator nPTB during skeletal muscle differentiation to control a potential network of splicing transitions. The results illustrate how two modes of posttranscriptional regulation combine to direct skeletal muscle development.

Indexed as

Alternative SplicingAnimalsCell DifferentiationMiceMicroRNAsMuscle DevelopmentMuscle, SkeletalPolypyrimidine Tract-Binding ProteinMicroRNAsPolypyrimidine Tract-Binding Protein

Identifiers

PMID17276332
OpenAlexW1998595844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.