ArticleThe Journal of clinical investigation2007
Transcriptional regulation of epithelial-mesenchymal transition.
Article in The Journal of clinical investigation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Population dynamics of EMT elucidates the timing and distribution of phenotypic intra-tumoral heterogeneity.iScience · 2023Article
- Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair.Science translational medicine · 2022Article
- Article
- The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis.Annals of dermatology · 2019Review
- TGF-β1 Signaling and Tissue Fibrosis.Cold Spring Harbor perspectives in biology · 2018Review
- Pathogenesis of Type 2 Epithelial to Mesenchymal Transition (EMT) in Renal and Hepatic Fibrosis.Journal of clinical medicine · 2015Review
- Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis.Nature medicine · 2015Article
- Hypoxia increases the abundance but not the assembly of extracellular fibronectin during epithelial cell transdifferentiation.Journal of cell science · 2015Article
- Regulation of breast cancer stem cell features.Contemporary oncology (Poznan, Poland) · 2015Review
- Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.Journal of experimental & clinical cancer research : CR · 2014Article
- Correlation between the overexpression of epidermal growth factor receptor and mesenchymal makers in endometrial carcinoma.Journal of gynecologic oncology · 2014Article
- Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model.Carcinogenesis · 2013Article
- Inhibition of Notch signaling by a γ-secretase inhibitor attenuates hepatic fibrosis in rats.PloS one · 2012Article
- Article
- Contribution of epithelial plasticity to renal transplantation-associated fibrosis.Transplantation proceedings · 2010Review
- Beyond epithelial to mesenchymal transition: a novel role for the transcription factor Snail in inflammation and wound healing.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2010Article
- Epithelial-to-mesenchymal transitions in the liver.Hepatology (Baltimore, Md.) · 2009Review
- Identification of progenitor cells that contribute to heterotopic skeletogenesis.The Journal of bone and joint surgery. American volume · 2009Article
- Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.Cancer research · 2008Article
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3 authors.
Funding
Abstract
It has become increasingly obvious that the notion of a terminally differentiated cell is likely a simplified concept. Epithelial-mesenchymal transition (EMT), during which epithelial cells assume a mesenchymal phenotype, is a key event occurring during normal development and pathological processes. Multiple extracellular stimuli and transcriptional regulators can trigger EMT, but how such distinct signaling pathways orchestrate the complex cellular events that facilitate EMT is not well understood. In this issue of the JCI, Venkov et al. report on their examination of fibroblasts resulting from EMT and describe a novel protein-DNA complex that is essential for transcription of fibroblast-specific protein 1 (FSP1) and sufficient to induce early EMT events (see the related article beginning on page 482). Collectively, their results suggest that this complex is an important regulator of the EMT transcriptome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.