ReviewJournal of applied genetics2007
Animal transgenesis: state of the art and applications.
Review in Journal of applied genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 98 citations in OpenAlex.
- A review of transgenic animal techniques and their applications.Journal, genetic engineering & biotechnology · 2023Review
- A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies.Nature biomedical engineering · 2022Article
- β-Glucanase specific expression in the intestine of transgenic pigs.Transgenic research · 2019Article
- Production of transgenic cattle by somatic cell nuclear transfer (SCNT) with the human granulocyte colony-stimulation factor (hG-CSF).Journal of animal science and technology · 2019Article
- Improvement of anti-nutritional effect resulting from β-glucanase specific expression in the parotid gland of transgenic pigs.Transgenic research · 2017Article
- Vascular alterations underlie developmental problems manifested in cloned cattle before or after birth.PloS one · 2015Article
- Production of recombinant human proinsulin in the milk of transgenic mice.Scientific reports · 2014Article
- Generation of AQP2-Cre transgenic mini-pigs specifically expressing Cre recombinase in kidney collecting duct cells.Transgenic research · 2014Article
- Space mutagenesis of genetically engineered bacteria expressing recombinant human interferon α1b and screening of higher yielding strains.World journal of microbiology & biotechnology · 2014Article
- Ethical issues of transplanting organs from transgenic animals into human beings.Cell journal · 2014Article
- Progress and prospects for genetic modification of nonhuman primate models in biomedical research.ILAR journal · 2013Review
- Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus.Transgenic research · 2011Article
- Precision genetics for complex objectives in animal agriculture.Journal of animal science · 2010Article
- Production of recombinant human erythropoietin/Fc fusion protein by genetically manipulated chickens.Transgenic research · 2010Article
- Transgene expression is associated with copy number and cytomegalovirus promoter methylation in transgenic pigs.PloS one · 2009Article
- Use of intracytoplasmic sperm injection (ICSI) to generate transgenic animals.Comparative immunology, microbiology and infectious diseases · 2009Review
- Transgenic mouse technology: principles and methods.Methods in molecular biology (Clifton, N.J.) · 2009Article
- Comparison of tetraploid blastocyst microinjection of outbred Crl:CD1(ICR), hybrid B6D2F1/Tac, and inbred C57BL/6NTac embryos for generation of mice derived from embryonic stem cells.Comparative medicine · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a constant expectation for fast improvement of livestock production and human health care products. The advent of DNA recombinant technology and the possibility of gene transfer between organisms of distinct species, or even distinct phylogenic kingdoms, has opened a wide range of possibilities. Nowadays we can produce human insulin in bacteria or human coagulation factors in cattle milk. The recent advances in gene transfer, animal cloning, and assisted reproductive techniques have partly fulfilled the expectation in the field of livestock transgenesis. This paper reviews the recent advances and applications of transgenesis in livestock and their derivative products. At first, the state of art and the techniques that enhance the efficiency of livestock transgenesis are presented. The consequent reduction in the cost and time necessary to reach a final product has enabled the multiplication of transgenic prototypes around the world. We also analyze here some emerging applications of livestock transgenesis in the field of pharmacology, meat and dairy industry, xenotransplantation, and human disease modeling. Finally, some bioethical and commercial concerns raised by the transgenesis applications are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.