ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2007
Health-related quality of life in HIV-1-infected patients on HAART: a five-years longitudinal analysis accounting for dropout in the APROCO-COPILOTE cohort (ANRS CO-8).
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta-analysis.BMC health services research · 2019Pooled it
- Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women.AIDS (London, England) · 2018Trial
- Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study.PloS one · 2015Trial
- Methadone induction in primary care (ANRS-Methaville): a phase III randomized intervention trial.BMC public health · 2012Trial
- A practical evaluation of statistical methods for the analysis of patient reported outcomes in an observational pharmaceutical study.PloS one · 2026Observational
- Article
- Factors associated with poorer quality of life in people living with HIV in southwestern France in 2018-2020 (ANRS CO3 AQUIVIH-NA cohort: QuAliV study).Scientific reports · 2023Article
- Factors associated with health-related quality of life in people living with HIV in Norway.Health and quality of life outcomes · 2023Article
- Factors affecting quality of life in adults with HIV: A local cross-sectional study.The South African journal of physiotherapy · 2023Article
- Health-related quality of life and associated factors among people living with HIV/AIDS in Sichuan, China: A cross-sectional study.Frontiers in public health · 2023Article
- Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Impact of Advanced HIV Disease on Quality of Life and Mortality in the Era of Combined Antiretroviral Treatment.Journal of clinical medicine · 2021Review
- Predictors of health-related quality of life among military HIV-infected individuals.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Correlates of health-related quality of life among adults receiving combination antiretroviral therapy in coastal Kenya.Health and quality of life outcomes · 2020Article
- Health-Related Quality of Life Among People Living with Human Immunodeficiency Virus on Highly Active Antiretroviral Therapy in Ethiopia: PROQOL-HIV Based Survey.Patient related outcome measures · 2020Article
- Changes and determinants of health-related quality of life among people newly diagnosed with HIV in China: a 1-year follow-up study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Health-related quality of life among military HIV patients on antiretroviral therapy.PloS one · 2017Article
- What determines health-related quality of life among people living with HIV: an updated review of the literature.Archives of public health = Archives belges de sante publique · 2014Article
- Socio-economic, behavioural, (neuro)psychological and clinical determinants of HRQoL in people living with HIV in Belgium: a pilot study.Journal of the International AIDS Society · 2013Article
- Impact of hepatitis B and C co-infection on health-related quality of life in HIV positive individuals.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
backgroundThe long-term efficacy of Highly Active Antiretroviral Therapies (HAART) has enlightened the crucial role of health-related quality of life (HRQL) among HIV-infected patients. However, any analysis of such extensive longitudinal data necessitates a suitable handling of dropout which may correlate with patients' health status.
methodsWe analysed the HRQL evolution over 5 years for 1,000 patients initiating a protease inhibitor (PI)-containing therapy, using MOS SF-36 physical (PCS) and mental (MCS) scores. In parallel with a classical separate random effects model, we used a joint parameter-dependent selection model to account for non-ignorable dropout.
resultsHRQL evolved according to a two-phase pattern, characterized by an initial improvement during the year following HAART initiation and a relative stabilization thereafter. Immunodepression and self-reported side effects were found to be negative predictors of both PCS and MCS scores. Hepatitis C virus coinfection and AIDS clinical stage were found to affect physical HRQL. Results were not significantly altered when accounting for dropout.
conclusionSuch results, obtained on a large sample of HIV-infected patients with extensive follow-up, underline the need for a regular monitoring of patients' immunological status and for a better management of their experience with hepatitis C and HAART.
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