Evidence map›Paper›PMID 17267686›Full record

ReviewMolecular biology of the cell2007

Functional symmetry of endomembranes.

Jaakko Saraste, Bruno Goud

Abstract readReview
In one paragraph

Review in Molecular biology of the cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. The Neuronal Golgi Network and Its Acolytes.Sub-cellular biochemistry · 2026
    Review
  5. The expanding organelle lipidomes: current knowledge and challenges.Cellular and molecular life sciences : CMLS · 2023
    Review
  6. Cellular Polarity Transmission to the Nucleus.Results and problems in cell differentiation · 2022
    Article
  7. The Golgi Apparatus and its Next-Door Neighbors.Frontiers in cell and developmental biology · 2022
    Review
  8. Article
  9. Article
  10. A New Look at the Functional Organization of the Golgi Ribbon.Frontiers in cell and developmental biology · 2019
    Article
  11. Review
  12. Review
  13. Spatial and Functional Aspects of ER-Golgi Rabs and Tethers.Frontiers in cell and developmental biology · 2016
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branching.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jaakko SarasteSection of Anatomy and Cell Biology, Department of Biomedicine, University of Bergen, N-5009 Bergen, Norway. jaakko.saraste@biomed.uib.no
Bruno Goud

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In higher eukaryotic cells pleiomorphic compartments composed of vacuoles, tubules and vesicles move from the endoplasmic reticulum (ER) and the plasma membrane to the cell center, operating in early biosynthetic trafficking and endocytosis, respectively. Besides transporting cargo to the Golgi apparatus and lysosomes, a major task of these compartments is to promote extensive membrane recycling. The endocytic membrane system is traditionally divided into early (sorting) endosomes, late endosomes and the endocytic recycling compartment (ERC). Recent studies on the intermediate compartment (IC) between the ER and the Golgi apparatus suggest that it also consists of peripheral ("early") and centralized ("late") structures, as well as a third component, designated here as the biosynthetic recycling compartment (BRC). We propose that the ERC and the BRC exist as long-lived "mirror compartments" at the cell center that also share the ability to expand and become mobilized during cell activation. These considerations emphasize the functional symmetry of endomembrane compartments, which provides a basis for the membrane rearrangements taking place during cell division, polarization, and differentiation.

Indexed as

Cell CompartmentationAnimalsEndocytosisEndoplasmic ReticulumGolgi ApparatusHumansIntracellular Membranesrab11 GTP-Binding Proteinsrab1 GTP-Binding Proteinsrab GTP-Binding Proteinsrab11 GTP-Binding Proteinsrab1 GTP-Binding Proteinsrab GTP-Binding Proteins

Identifiers

PMID17267686
PMCPMC1839002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.