ArticlePostgraduate medical journal2007
Inappropriate prescribing of proton pump inhibitors in primary care.
Article in Postgraduate medical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Head of bed elevation to relieve gastroesophageal reflux symptoms: a systematic review.BMC family practice · 2021Pooled it
- Pooled it
- Meta-analysis: proton pump inhibitors moderately increase the risk of small intestinal bacterial overgrowth.Journal of gastroenterology · 2018Pooled it
- Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline.Canadian family physician Medecin de famille canadien · 2017Guideline
- Effectiveness of Interventions to Deprescribe Inappropriate Proton Pump Inhibitors in Older Adults.Drugs & aging · 2017Pooled it
- Pooled it
- Interventions that can reduce inappropriate prescribing in the elderly: a systematic review.Drugs & aging · 2009Pooled it
- Low-value chronic prescription of acid reducing medication among Dutch general practitioners: impact of a patient education intervention.BMC primary care · 2024Trial
- Cognitive impact after short-term exposure to different proton pump inhibitors: assessment using CANTAB software.Alzheimer's research & therapy · 2015Trial
- Prescription peer academic detailing to reduce inappropriate prescribing for older patients: a cluster randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013Trial
- An automated tool for detecting medication overuse based on the electronic health records.Pharmacoepidemiology and drug safety · 2013Trial
- Outcomes of a decision support prompt in community pharmacy-dispensing software to promote step-down of proton pump inhibitor therapy.British journal of clinical pharmacology · 2011Trial
- Deprescribing of proton pump inhibitors in internal medicine in-patients: A retrospective observational study.Exploratory research in clinical and social pharmacy · 2026Article
- Appropriate Use of Proton Pump Inhibitors in General Out Patient Department of a Tertiary Care Center of Kathmandu Valley: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Omeprazole and Risk of Hypertension: Analysis of Existing Literature and the WHO Global Pharmacovigilance Database.Drugs - real world outcomes · 2024Article
- Nurse-led medication management as a critical component of transitional care for preventing drug-related problems.Aging clinical and experimental research · 2024Review
- Determinants of and interventions for Proton Pump Inhibitor prescription behavior: A systematic scoping review.BMC primary care · 2024Article
- Impact of large scale, multicomponent intervention to reduce proton pump inhibitor overuse in integrated healthcare system: difference-in-difference study.BMJ (Clinical research ed.) · 2024Article
- Evaluation of gastroprotectant administration in hospitalized cats in a tertiary referral hospital.Journal of feline medicine and surgery · 2023Article
- Proton pump inhibitors and dementia: what association?Dementia & neuropsychologia · 2023Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine if an educational intervention initiated in secondary care can influence prescribing of proton pump inhibitors (PPIs) in the community.
methodsA prospective study of PPI use in patients admitted to medical wards in a university hospital. A simple educational intervention was employed to reduce inappropriate prescribing of PPIs in the community.
resultsIn the pre-intervention analysis 66/271 (24%) patients were receiving treatment with a PPI prescribed in the community. In 36/66 (54%) patients the PPI had been prescribed inappropriately. Six months after the intervention 91/344 (26%) patients were prescribed a PPI in the community. In only 45 of these 91 (49%) patients was there a recommended indication.
conclusionThe intervention used in this study had no effect on the proportion of patients taking a PPI at the time of hospital admission or on the appropriateness of prescribing in the community.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.