Evidence map›Paper›PMID 17265142›Full record

ArticleVirus genes2007

Sequence and phylogenetic analysis of the S1 genome segment of turkey-origin reoviruses.

J Michael Day, Mary J Pantin-Jackwood, Erica Spackman

Abstract read
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In one paragraph

Article in Virus genes, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

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  9. Genomic characterization of a turkey reovirus field strain by Next-Generation Sequencing.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J Michael DaySoutheast Poultry Research Laboratory, USDA-ARS, 934 College Station Road, Athens, GA 30605, USA.
Mary J Pantin-Jackwood
Erica Spackman
U.S. National Poultry Research Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on previous reports characterizing the turkey-origin avian reovirus (TRV) sigmaB (sigma2) major outer capsid protein gene, the TRVs may represent a new group within the fusogenic orthoreoviruses. However, no sequence data from other TRV genes or genome segments has been reported. The sigmaC protein encoded by the avian reovirus S1 genome segment is the cell attachment protein and a major antigenic determinant for avian reovirus. The chicken reovirus S1 genome segment is well characterized and is well conserved in viruses from that species. This report details the amplification, cloning and sequencing of the entire S1 genome segment from two and the entire coding sequences of the sigmaC, p10 and p17 genes from an additional five TRVs. Sequence analysis reveals that of the three proteins encoded by the TRV S1 genome segment, sigmaC shares at most 57% amino acid identity with sigmaC from the chicken reovirus reference strain S1133, while the most similar p10 and p17 proteins share 72% and 61% identity, respectively, with the corresponding S1133 proteins. The most closely related mammalian reovirus, the fusogenic Nelson Bay reovirus, encodes a sigmaC protein that shares from 25% to 28% amino acid identity with the TRV sigmaC proteins. This report supports the earlier suggestion that the TRVs are a separate virus species within the Orthoreovirus genus, and may provide some insight into TRV host specificity and pathogenesis.

Indexed as

Genome, ViralPhylogenySequence Analysis, ProteinAmino Acid SequenceAnimalsChickensChlorocebus aethiopsMolecular Sequence DataOrthoreovirus, AvianPoultryQuailSequence Analysis, DNATurkeysVero Cells

Identifiers

PMID17265142
OpenAlexW2075790440

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.