ReviewThe Journal of membrane biology2006
Genomic organization of the mammalian SLC14a2 urea transporter genes.
Review in The Journal of membrane biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Urea functions as a risk signal driving astrocyte-mediated neuroinflammation following stroke.Journal of neuroinflammation · 2025Article
- Aging increases UT-B urea transporter protein abundance in brains of male mice.Physiological reports · 2025Article
- Genes and Evolution of Urea Transporters.Sub-cellular biochemistry · 2025Review
- Identification and characterisation of de novo germline structural variants in two commercial pig lines using trio-based whole genome sequencing.BMC genomics · 2023Article
- The role of rumen epithelial urea transport proteins in urea nitrogen salvage: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Review
- A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure.Kidney international · 2020Article
- Hyperosmolality regulates UT-A6 urea transporter expression in the Caco-2 cell line.Physiological reports · 2016Article
- Urea transporter proteins as targets for small-molecule diuretics.Nature reviews. Nephrology · 2015Review
- Urea transporter UT-B deletion induces DNA damage and apoptosis in mouse bladder urothelium.PloS one · 2013Article
- Mice lacking urea transporter UT-B display depression-like behavior.Journal of molecular neuroscience : MN · 2012Article
- Urea transporter physiology studied in knockout mice.Frontiers in physiology · 2012Article
- The emerging physiological roles of the SLC14A family of urea transporters.British journal of pharmacology · 2011Review
- Vasopressin increases phosphorylation of Ser84 and Ser486 in Slc14a2 collecting duct urea transporters.American journal of physiology. Renal physiology · 2010Article
- Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.BMC medical genomics · 2009Article
- Oligomeric structure and functional characterization of the urea transporter from Actinobacillus pleuropneumoniae.Journal of molecular biology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urea transporters encoded by the UT-A gene play fundamental roles in the kidney and possibly other tissues. Knowledge of the genomic organization of the mouse, rat and human UT-A genes has enabled the engineering of transgenic and knockout animals and these have helped refine our understanding of the role of UT-A proteins. This review summarizes the published work that has accrued on the structure and regulation of these genes. It also documents a novel cDNA, human UT-A3, which has enabled a major refinement of the human UT-A gene structure. This and other information contained in this review should prove useful for future comparative genomic analysis, studies addressing gene regulation and for the engineering of transgenic and knockout animal strains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.