Evidence map›Paper›PMID 17264247›Full record

ArticleJournal of clinical pathology2007

Children's vaccines do not induce cross reactivity against SARS-CoV.

Yang Yu, Huali Jin, Ze Chen, Qingling L Yu, Yijie J Ma, Xiaolin L Sun, Bin Wang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical pathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Managing children with brain tumors during the COVID-19 era: Don't stop the care!Computational and structural biotechnology journal · 2021
    Review
  5. Coronavirus Disease 2019 in Children.Frontiers in pediatrics · 2021
    Review
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  7. Article
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  9. Review
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yang YuState Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, China.
Huali Jin
Ze Chen
Qingling L Yu
Yijie J Ma
Xiaolin L Sun
Bin Wang
China Agricultural University · CNFudan University · CNWuhan Institute of Virology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.

Indexed as

AnimalsAntibodies, ViralChildChild, PreschoolCross ReactionsEnzyme-Linked Immunosorbent AssayHumansImmune SeraImmunizationInfantMiceMice, Inbred C57BLSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusT-LymphocytesVaccinesAntibodies, ViralImmune SeraVaccines

Identifiers

PMID17264247
PMCPMC1860633
OpenAlexW2011920846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.