ArticleDrugs1991
Coronary disease and stroke in patients with large-vessel peripheral arterial disease.
Article in Drugs, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Etiology and Prevalence of Peripheral Arterial Disease
Natural History of Peripheral Arterial Disease
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- The prognosis of non-critical limb ischaemia: a systematic review of population-based evidence.The British journal of general practice : the journal of the Royal College of General Practitioners · 1999Pooled it
- Oxidative Stress in Peripheral Arterial Disease (PAD) Mechanism and Biomarkers.Antioxidants (Basel, Switzerland) · 2019Review
- Regional intensity of vascular care and lower extremity amputation rates.Journal of vascular surgery · 2013Article
- Variation in the use of lower extremity vascular procedures for critical limb ischemia.Circulation. Cardiovascular quality and outcomes · 2012Article
- Effects of peripheral arterial disease on outcomes in advanced chronic systolic heart failure: a propensity-matched study.Circulation. Heart failure · 2010Article
- Prevalence of abnormal ankle brachial index in patients with primary Sjogren's syndrome.Clinical rheumatology · 2009Article
- Progression of peripheral arterial disease predicts cardiovascular disease morbidity and mortality.Journal of the American College of Cardiology · 2008Article
- Ten year cerebrovascular morbidity and mortality in 68 year old men with asymptomatic carotid stenosis.BMJ (Clinical research ed.) · 1995Article
- Peripheral artery disease and non-coronary atherosclerosis in Hispanics: another paradox?Progress in cardiovascular diseasesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Previous reports have indicated an excess of mortality from coronary heart disease (CHD), cardiovascular disease (CVD), and all causes in subjects with large-vessel peripheral arterial disease (LV-PAD). However, there is little information available concerning the risk of nonfatal events (morbidity) in this patient group. In a population-based study of 67 patients with LV-PAD and 408 control subjects without this condition, nonfatal CHD and stroke, and total CVD events, morbidity and mortality were evaluated in both men and women. Those with LV-PAD had a 3-fold excess of CVD morbidity at baseline compared with control subjects of the same sex. However, the absolute CVD rates were greater in men than women. During the 10 years of follow-up, women with LV-PAD had more nonfatal CVD events than men, resulting in comparable overall morbidity rates. In logistic regression models adjusted for other CVD risk factors, total CVD morbidity and mortality combined with 2.5 times as great in men and 5 times as great in women with LV-PAD as in those without peripheral arterial disease. These results suggest that the total morbidity and mortality burden are dramatically increased in both men and women with LV-PAD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.