ArticleJournal of perinatology : official journal of the California Perinatal Association2007
High flow nasal cannula versus nasal CPAP for neonatal respiratory disease: a retrospective study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Humidified High Flow Nasal Cannula to Nasal Continuous Positive Airway Pressure for Non-Invasive Respiratory Support in Neonates
High Flow Nasal Cannula vs Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation
Humidified High Flow Nasal Cannula Versus Nasal Intermittent Positive Ventilation in Neonates as Primary Respiratory Support:a Randomized Controlled Trial
Adaptive Dynamic Inspiratory Nasal Apparatus (ADINA): Comparison to High Flow Nasal Cannula (HFNC)
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 175 citations in OpenAlex.
- A Systematic Review of the High-flow Nasal Cannula for Adult Patients.Critical care (London, England) · 2018Pooled it
- High flow nasal cannula for respiratory support in preterm infants.The Cochrane database of systematic reviews · 2016Pooled it
- Strategies for the discontinuation of humidified high flow nasal cannula (HHFNC) in preterm infants.The Cochrane database of systematic reviews · 2015Pooled it
- High-flow nasal cannula therapy for respiratory support in children.The Cochrane database of systematic reviews · 2014Pooled it
- Nasal highflow improves ventilation in patients with COPD.International journal of chronic obstructive pulmonary disease · 2016Trial
- Trial
- High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities.Journal of perinatology : official journal of the California Perinatal Association · 2010Trial
- High-Flow Nasal Cannula in COVID-19 Patients With Moderate to Severe Respiratory Distress: A Retrospective Analysis.Cureus · 2024Article
- Medical Treatment of Obstructive Sleep Apnea in Children.Journal of clinical medicine · 2023Review
- The Impact of High-Flow Nasal Cannula Therapy on Acute Respiratory Distress Syndrome Patients: A Systematic Review.Cureus · 2023Review
- High-Flow Nasal Cannula oxygen therapy in COVID-19: retrospective analysis of clinical outcomes - single center experience.Frontiers in medicine · 2023Article
- High-flow nasal cannula therapy in a predominantly African American population with COVID-19 associated acute respiratory failure.BMJ open respiratory research · 2021Article
- Improving clinical outcomes of very low birth weight infants: Implementation of standardized management guidelines in tertiary care hospital in Haryana.International journal of pediatrics & adolescent medicine · 2020Article
- High-Flow, Heated, Humidified Air Via Nasal Cannula Treats CPAP-Intolerant Children With Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017Article
- Consensus approach to nasal high-flow therapy in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- Robin sequence: what the multidisciplinary approach can do.Journal of multidisciplinary healthcare · 2017Review
- High Flow Nasal Cannulae versus Nasal Continuous Positive Airway Pressure in Neonates with Respiratory Distress Syndrome Managed with INSURE Method: A Randomized Clinical Trial.Iranian journal of medical sciences · 2016Article
- Respiratory support with heated humidified high flow nasal cannula in preterm infants.Korean journal of pediatrics · 2016Review
- Weaning preterm infants from continuous positive airway pressure: evidence for best practice.World journal of pediatrics : WJP · 2015Review
- Unraveling the Links Between the Initiation of Ventilation and Brain Injury in Preterm Infants.Frontiers in pediatrics · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOur objective is to assess the frequency of usage, safety and clinical utility of humidified high flow nasal cannula (HHFNC) in two tertiary care hospitals and compare outcomes to a historical control group of premature infants who received nasal continuous positive airway pressure (NCPAP). STUDY
designThe first part of the study describes the increased HHFNC usage in two tertiary neonatal intensive care units. The second part compares outcomes of infants, born at less than 30 weeks gestation, who received either NCPAP or HHFNC as an early respiratory support mode.
resultsHHFNC usage increased (64%) after its introduction in infants of all gestational ages whereas the usage of NCPAP decreased from 19 to 4%. Ninety-five percent of infants born at less than 30 weeks gestation received HHFNC at some point during their hospital stay whereas only 12% received NCPAP. There were no differences in death or bronchopulmonary dysplasia (BPD), but ventilator-days per patient were decreased (19.4 to 9.9) following introduction of HHFNC. Comparing the cohort of infants who received either NCPAP or HHFNC as an early mode of respiratory support, there were no differences in deaths, ventilator-days, BPD, blood infections or other outcomes. More infants were intubated for failing early NCPAP compared to early HHFNC (40 to 18%).
conclusionsHHFNC was well-tolerated by premature infants. Compared to infants managed with NCPAP, there were no apparent differences in adverse outcomes following the introduction of HHFNC. Additional research is needed to better define the utility and safety of HHFNC compared to NCPAP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.