Gating rings formed by RCK domains: keys to gate opening.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed.

1. Calcium-Activated KHandbook of experimental pharmacology · 2021
   Article
2. Calcium-driven regulation of voltage-sensing domains in BK channels.eLife · 2019
   Article
3. Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel.The Journal of general physiology · 2017
   Review
4. Understanding the conformational motions of RCK gating rings.The Journal of general physiology · 2017
   Review
5. The Ca2+-activated K+ current of human sperm is mediated by Slo3.eLife · 2014
   Article
6. State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels.Proceedings of the National Academy of Sciences of the United States of America · 2013
   Article
7. BK Channels in Cardiovascular Diseases and Aging.Aging and disease · 2013
   Article
8. Barium ions selectively activate BK channels via the Ca2+-bowl site.Proceedings of the National Academy of Sciences of the United States of America · 2012
   Article
9. Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region.Proceedings of the National Academy of Sciences of the United States of America · 2011
   Article
10. Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus.The Journal of biological chemistry · 2011
    Article
11. Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel.The Journal of physiology · 2010
    Review
12. The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangements.The Journal of general physiology · 2010
    Article
13. Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+.The Journal of general physiology · 2010
    Article
14. Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
15. Modulation of the conductance-voltage relationship of the BK(Ca) channel by shortening the cytosolic loop connecting two RCK domains.Biophysical journal · 2009
    Article
16. Regulation of bestrophin Cl channels by calcium: role of the C terminus.The Journal of general physiology · 2008
    Article
17. Modulation of the conductance-voltage relationship of the BK Ca channel by mutations at the putative flexible interface between two RCK domains.Biophysical journal · 2008
    Article
18. The RCK2 domain of the human BKCa channel is a calcium sensor.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
19. Mg2+-dependent regulation of BK channels: importance of electrostatics.The Journal of general physiology · 2008
    Article

Corrections and comments

• Comment on
  Gating and inward rectifying properties of the MthK K+ channel with and without the gating ring.2007

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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