Evidence map›Paper›PMID 17261579›Full record

ArticleArchives of disease in childhood2007

Children with pneumonia: how do they present and how are they managed?

Julia E Clark, Donna Hammal, David Spencer, Fiona Hampton

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Archives of disease in childhood, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Guideline
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  4. [Pneumonia in childhood and adolescence].Radiologie (Heidelberg, Germany) · 2025
    Review
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  16. When and how do GPs record vital signs in children with acute infections? A cross-sectional study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Julia E ClarkDepartment of Paediatric Infectious Disease, Newcastle General Hospital, Newcastle, UK. Julia.clark@nuth.nhs.uk
Donna Hammal
David Spencer
Fiona Hampton
Freeman Hospital · GBJames Cook University Hospital · GBNorth Tyneside General Hospital · GBRoyal Victoria Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the spectrum of clinical features and management of community acquired pneumonia in the UK.

designProspectively recorded clinical details for all children with possible pneumonia and chest x ray (CXR) changes in 13 hospitals in the North of England between 2001 and 2002.

results89% of 711 children presenting to hospital with pneumonia were admitted; 96% received antibiotics, 70% intravenously. 20% had lobar CXR changes, 3% empyema and 4% required intensive care. Respiratory rate (RR), hypoxia and dyspnoea all correlated with each other and prompted appropriate interventions. Admission in children, not infants, was independently associated with RR, oxygen saturation, lobar CXR changes and pyrexia. Neither C-reactive protein, lobar CXR changes or pyrexia were associated with severity. Children over 1 year old with perihilar CXR changes more often had severe disease (p = 0.001). Initial intravenous antibiotics were associated with lobar CXR changes in infants and children and with dyspnoea, pyrexia and pleural effusion in children. The presence of pleural effusion increased duration of antibiotic treatment (p<0.001). Cefuroxime was the most often used intravenous antibiotic in 61%. Oral antibiotics included a penicillin in 258 (46%), a macrolide in 192 (34%) and a cephalosporin in 117 (21%). Infants stayed significantly longer (p<0.001) as did children with severe disease (p<0.01), effusions (p = 0.005) or lobar CXR changes (p< or =0.001).

conclusionsThere is a high rate of intravenous antibiotic administration in hospital admissions for pneumonia. Despite lobar CXR changes not being independently associated with severe disease, initial lobar CXR changes and clinical assessment in children independently influenced management decisions, including admission and route of antibiotics.

Indexed as

AdolescentAnti-Bacterial AgentsBiomarkersChildChild, PreschoolCommunity-Acquired InfectionsC-Reactive ProteinDrug Administration ScheduleEnglandFemaleHospitalizationHumansInfantInfant, NewbornInjections, IntravenousLength of StayAnti-Bacterial AgentsBiomarkersC-Reactive ProteinOxygen

Identifiers

PMID17261579
PMCPMC2083747
OpenAlexW2011732705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.