ArticleJournal of the American Chemical Society2007
Fluorescent DNA nanotags: supramolecular fluorescent labels based on intercalating dye arrays assembled on nanostructured DNA templates.
Article in Journal of the American Chemical Society, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed.
- Light-Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Target-Responsive DNA Hydrogels with Encapsulation and Release Properties Using Programmable CRISPR-Cas12a.ACS chemical biology · 2025Article
- DNA-Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties.Angewandte Chemie (International ed. in English) · 2024Article
- Pursuing excitonic energy transfer with programmable DNA-based optical breadboards.Chemical Society reviews · 2023Review
- Interfacing DNA nanotechnology and biomimetic photonic complexes: advances and prospects in energy and biomedicine.Journal of nanobiotechnology · 2022Review
- Review
- Bead-Immobilized Multimodal Molecular Beacon-Equipped DNA Machinery for Specific RNA Target Detection: A Prototypical Molecular Nanobiosensor.Nanomaterials (Basel, Switzerland) · 2021Article
- Molecular structure, DNA binding mode, photophysical properties and recommendations for use of SYBR Gold.Nucleic acids research · 2021Article
- DNA Nanostructures in the Fight Against Infectious Diseases.Advanced nanobiomed research · 2021Article
- Structural and Photophysical Templating of Conjugated Polyelectrolytes with Single-Stranded DNA.Chemistry of materials : a publication of the American Chemical Society · 2020Article
- Nanosheets and 2D-nanonetworks by mutually assisted self-assembly of fullerene clusters and DNA three-way junctions.Nanoscale advances · 2019Article
- Increased Flexibility between Stems of Intramolecular Three-Way Junctions by the Insertion of Bulges.Biophysical journal · 2018Article
- Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies.Angewandte Chemie (International ed. in English) · 2018Review
- Pentafluorobenzene end-group as a versatile handle forChemical science · 2017Article
- Enhancement of RecA-mediated self-assembly in DNA nanostructures through basepair mismatches and single-strand nicks.Scientific reports · 2017Article
- Protein-Sized Bright Fluorogenic Nanoparticles Based on Cross-Linked Calixarene Micelles with Cyanine Corona.Angewandte Chemie (International ed. in English) · 2016Article
- Mechanisms of small molecule-DNA interactions probed by single-molecule force spectroscopy.Nucleic acids research · 2016Article
- Metal-responsive structural transformation between artificial DNA duplexes and three-way junctions.Chemical science · 2016Article
- Supramolecular polymer formation by cyclic dinucleotides and intercalators affects dinucleotide enzymatic processing.Future science OA · 2016Article
- Bright Fluorescent Nanotags from Bottlebrush Polymers with DNA-Tipped Bristles.ACS central science · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Fluorescence detection and imaging are vital technologies in the life sciences and clinical diagnostics. The key to obtaining high-resolution images and sensitive detection is to use fluorescent molecules or particles that absorb and emit visible light with high efficiency. We have synthesized supramolecular complexes consisting of a branched DNA template and fluorogenic intercalating dyes. Because dyes can intercalate up to every other base pair, high densities of fluorophores are assembled yet the DNA template keeps them far enough away from each other to prevent self-quenching. The efficiency with which these noncovalent assemblies absorb light is more than 10-fold greater than that of the individual dye molecules. Förster resonance energy transfer from the intercalated dyes to covalently attached acceptor dyes is very efficient, allowing for wavelength shifting of the emission spectrum. Simple biotinylation of the DNA template allows for labeling of streptavidin-coated synthetic microspheres and mouse T-cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.