Evidence map›Paper›PMID 17251927›Full record

ArticleEuropean journal of clinical nutrition2007

Limited evidence for effects of diet for type 2 diabetes from systematic reviews.

F A van de Laar, R P Akkermans, J J van Binsbergen

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Article in European journal of clinical nutrition, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Diet, delusion and diabetes.Diabetologia · 2009
    Article
  4. Article
4 · The record

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5 · Who and what money

Authors and funding

3 authors.

F A van de LaarDepartment of General Practice, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands. f.vandelaar@hag.umcn.nl
R P Akkermans
J J van Binsbergen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSystematic reviews are an appraised method to summarize research in a concise and transparent way, and may enable to draw conclusions beyond the sum of results of individual studies. We assessed the results, quality and external validity of systematic reviews on diet in patients with type 2 diabetes. DESIGN, SETTING, SUBJECTS: We systematically searched for systematic reviews on nutritional interventions in patients with type 2 diabetes that used a reproducible search strategy in at least one major database that applied some form of quality assessment. We assessed quality and the external validity of the retrieved systematic reviews. Outcomes were defined as statistical meta-analyses or narrative results using a predefined and reproducible method.

resultsSix systematic reviews met the inclusion criteria, investigating dietary interventions in general (n=3), chromium supplementation (n=1), fish-oil (n=1) or herbs and nutrition supplements (n=1). Quality assessment showed minimal/minor flaws in four cases and major/extensive flaws in two cases. All reviews had insufficient data needed to judge external validity. In reviews with minimal/minor flaws, we found beneficial effects of very-low-calorie diets and fish-oil supplements. However, the external validity of these results could not be assessed sufficiently.

conclusionsSystematic reviews largely failed to produce knowledge beyond the sum of the original studies. Furthermore, judgment of external validity was hampered in most cases owing to missing data. To improve the quality and usefulness of systematic reviews of dietary interventions, we recommend the application of more focused research questions, but with broader inclusion criteria, for example, the use of observational studies. SPONSORSHIP: Internal funding Radboud University Nijmegen Medical Centre.

Indexed as

Diet, ReducingMeta-Analysis as TopicReview Literature as TopicBody Mass IndexDiabetes Mellitus, Type 2Dietary SupplementsEvidence-Based MedicineFemaleHumansMaleReproducibility of ResultsResearchTreatment Outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.