ArticleEuropean journal of nuclear medicine and molecular imaging2007
Validation of a new cardiac image fusion software for three-dimensional integration of myocardial perfusion SPECT and stand-alone 64-slice CT angiography.
Article in European journal of nuclear medicine and molecular imaging, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Integrated SPECT/CT for assessment of haemodynamically significant coronary artery lesions in patients with acute coronary syndrome.European journal of nuclear medicine and molecular imaging · 2011Trial
- Non-invasive assessment of coronary artery disease with CT coronary angiography and SPECT: a novel dose-saving fast-track algorithm.European journal of nuclear medicine and molecular imaging · 2010Trial
- A deep-learning-based pipeline for automatic fusion of CT coronary angiogram and stress perfusion CMR.Medical physics · 2026Article
- A Novel and Simplified MSI Approach to Predicting the Long-term Cardiac Function of STEMI.Current medical imaging · 2025Article
- EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2021Article
- Rationale and design of the quantification of myocardial blood flow using dynamic PET/CTA-fused imagery (DEMYSTIFY) to determine physiological significance of specific coronary lesions.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Observational
- Multimodal Multiparametric Three-dimensional Image Fusion in Coronary Artery Disease: Combining the Best of Two Worlds.Radiology. Cardiothoracic imaging · 2020Article
- Hemodynamic impact of coronary stenosis using computed tomography: comparison between noninvasive fractional flow reserve and 3D fusion of coronary angiography with stress myocardial perfusion.The international journal of cardiovascular imaging · 2019Article
- Fusion of Three-Dimensional Echocardiographic Regional Myocardial Strain with Cardiac Computed Tomography for Noninvasive Evaluation of the Hemodynamic Impact of Coronary Stenosis in Patients with Chest Pain.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2018Article
- Fusion of CT coronary angiography and whole-heart dynamic 3D cardiac MR perfusion: building a framework for comprehensive cardiac imaging.The international journal of cardiovascular imaging · 2018Article
- Diagnostic performance of hybrid cardiac SPECT/CT imaging for patients with takotsubo cardiomyopathy.European journal of hybrid imaging · 2018Article
- Non-invasive assessment of the haemodynamic significance of coronary stenosis using fusion of cardiac computed tomography and 3D echocardiography.European heart journal. Cardiovascular Imaging · 2017Article
- 3D SPECT/CT fusion using image data projection of bone SPECT onto 3D volume-rendered CT images: feasibility and clinical impact in the diagnosis of bone metastasis.Annals of nuclear medicine · 2017Article
- Infarct characterization using CT.Cardiovascular diagnosis and therapy · 2017Review
- Hybrid CCTA/SPECT myocardial perfusion imaging findings in patients with anomalous origin of coronary arteries from the opposite sinus and suspected concomitant coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Recent Advances in Nuclear Cardiology.Nuclear medicine and molecular imaging · 2016Review
- Multicentre multi-device hybrid imaging study of coronary artery disease: results from the EValuation of INtegrated Cardiac Imaging for the Detection and Characterization of Ischaemic Heart Disease (EVINCI) hybrid imaging population.European heart journal. Cardiovascular Imaging · 2016Article
- Article
- Cardiac hybrid imaging.European journal of nuclear medicine and molecular imaging · 2014Review
- Automatic detection of left and right ventricles from CTA enables efficient alignment of anatomy with myocardial perfusion data.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
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11 authors.
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Abstract
purposeCombining the functional information of SPECT myocardial perfusion imaging (SPECT-MPI) and the morphological information of coronary CT angiography (CTA) may allow easier evaluation of the spatial relationship between coronary stenoses and perfusion defects. The aim of the present study was the validation of a novel software solution for three-dimensional (3D) image fusion of SPECT-MPI and CTA.
methodsSPECT-MPI with adenosine stress/rest 99mTc-tetrofosmin was fused with 64-slice CTA in 15 consecutive patients with a single perfusion defect and a single significant coronary artery stenosis (>or=50% diameter stenosis). 3D fused SPECT/CT images were analysed by two independent observers with regard to superposition of the stenosed vessel onto the myocardial perfusion defect. Interobserver variability was assessed by recording the X, Y, Z coordinates for the origin of the stenosed coronary artery and the centre of the perfusion defect and measuring the distance between the two landmarks.
resultsSPECT-MPI revealed a fixed defect in seven patients, a reversible defect in five patients and a mixed defect in three patients and CTA documented a significant stenosis in the respective subtending coronary artery. 3D fused SPECT/CT images showed a match of coronary lesion and perfusion defect in each patient and the fusion process took less than 15 min. Interobserver variability was excellent for landmark detection (r = 1.00 and r = 0.99, p < 0.0001) and very good for the 3D distance between the two landmarks (r = 0.94, p < 0.001).
conclusion3D SPECT/CT image fusion is feasible, reproducible and allows correct superposition of SPECT segments onto cardiac CT anatomy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.