ArticlePloS one2007
Lack of association between Y-chromosomal haplogroups and prostate cancer in the Korean population.
Article in PloS one, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry.Human genetics · 2012Pooled it
- Y Chromosome Haplogroups and Susceptibility to Esophageal Squamous Cell Carcinoma: An Exploratory Association and Diagnostic Modeling Study.Molecular genetics & genomic medicine · 2026Article
- Article
- Origin of ethnic groups, linguistic families, and civilizations in China viewed from the Y chromosome.Molecular genetics and genomics : MGG · 2021Review
- A review of studies examining the association between genetic biomarkers (short tandem repeats and single-nucleotide polymorphisms) and risk of prostate cancer: the need for valid predictive biomarkers.Prostate international · 2020Review
- The Y-chromosome F haplogroup contributes to the development of Barrett's esophagus-associated esophageal adenocarcinoma in a white male population.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2020Article
- Identification of specific Y chromosomes associated with increased prostate cancer risk.The Prostate · 2014Article
- Fate of the human Y chromosome linked genes and loci in prostate cancer cell lines DU145 and LNCaP.BMC genomics · 2013Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The Y chromosome has recently been suggested to have an association with prostate cancer risk in human populations. Since this chromosome is haploid and lacks recombination over most of its length, haplotypes constructed from binary markers throughout the chromosome can be used for association studies. To assess the possible Y-chromosomal contribution to prostate cancer risk, we have therefore analyzed 14 Y-chromosomal binary markers in 106 prostate cancer cases and 110 controls from the Korean population. In contrast to previous findings in the Japanese population, no statistically significant difference in the distribution of Y-chromosomal haplogroup frequencies was observed between the case and control groups of Koreans. Thus, our data imply that the previously reported associations between Y-chromosomal lineages and a predisposition to, or protection against, prostate cancer might be explained by statistical fluctuations, or by genetic effects that are seen only in some environments.
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