ReviewGenetics2007
Applications of high-throughput RNA interference screens to problems in cell and developmental biology.
Review in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed.
- Genome-scale transcriptional activation by non-homologous end joining-mediated integration in Yarrowia lipolytica.Biotechnology for biofuels and bioproducts · 2024Article
- Review
- RNAi turns 25:contributions and challenges in insect science.Frontiers in insect science · 2023Review
- Imaging of In Vitro and In Vivo Neurons in Drosophila Using Stochastic Optical Reconstruction Microscopy.Current protocols · 2021Article
- Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening.Scientific reports · 2019Article
- A Cell-based Assay to Investigate Non-muscle Myosin II Contractility via the Folded-gastrulation Signaling Pathway in Drosophila S2R+ Cells.Journal of visualized experiments : JoVE · 2018Article
- Article
- Defense Mechanisms against Viral Infection inViruses · 2018Review
- Article
- RNAi screening in Drosophila cells and in vivo.Methods (San Diego, Calif.) · 2014Review
- Development of a Drosophila cell-based error correction assay.Frontiers in oncology · 2013Article
- A genome-wide systematic analysis reveals different and predictive proliferation expression signatures of cancerous vs. non-cancerous cells.PLoS genetics · 2013Article
- Bottlenecks caused by software gaps in miRNA and RNAi research.Pharmaceutical research · 2012Article
- DroPNet: a web portal for integrated analysis of Drosophila protein-protein interaction networks.Nucleic acids research · 2012Article
- In situ electroporation of surface-bound siRNAs in microwell arrays.Lab on a chip · 2012Article
- Deconstructing host-pathogen interactions in Drosophila.Disease models & mechanisms · 2012Review
- Fine-tuning of the Msn2/4-mediated yeast stress responses as revealed by systematic deletion of Msn2/4 partners.Molecular biology of the cell · 2011Article
- In vivo RNAi: today and tomorrow.Cold Spring Harbor perspectives in biology · 2010Review
- Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities.BMC bioinformatics · 2010Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
RNA interference (RNAi) in tissue culture cells has emerged as an excellent methodology for identifying gene functions systematically and in an unbiased manner. Here, we describe how RNAi high-throughput screening (HTS) in Drosophila cells are currently being performed and emphasize the strengths and weaknesses of the approach. Further, to demonstrate the versatility of the technology, we provide examples of the various applications of the method to problems in signal transduction and cell and developmental biology. Finally, we discuss emerging technological advances that will extend RNAi-based screening methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.