Evidence map›Paper›PMID 17243754›Full record

ArticleNano letters2007

A simple DNA-based translation system.

Alejandra V Garibotti, Shiping Liao, Nadrian C Seeman

Abstract read
In one paragraph

Article in Nano letters, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alejandra V GaribottiDepartment of Chemistry, New York University, New York, New York 10003, USA.
Shiping Liao
Nadrian C Seeman

Funding

Physical Chemistry of Recombinational IntermediatesR37GM029554 · NIGMS · NEW YORK UNIVERSITY · PI SEEMAN, NADRIAN C. · 2005 to 2012
$2.7M
PHYSICAL CHEMISTRY OF RECOMBINATIONAL INTERMEDIATESR01GM029554 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI SEEMAN, NADRIAN C. · 1985 to 2004
$1.4M
NIGMS NIH HHS GM-29554NIGMS NIH HHS R01 GM029554NIGMS NIH HHS R37 GM029554
6 · The paper itself

Abstract

We have used DNA double crossover (DX) molecules to produce a translation system that generates unique molecular products. The particular species of DX molecule used contains an even number of half-turns between crossover points, so there is a continuous strand on both sides of the molecule. One of these strands acts as the input strand containing the message, and a second strand acts as the product of translation. The crossover strands carry the "code" that connects the two sides of the molecule. This system is more robust, more extendable, and simpler than previous DNA-based translation systems that have been reported. It is designed to be useful in a variety of applications that utilize the concept of translating from one code to another.

Indexed as

Computers, MolecularProtein BiosynthesisBiomechanical PhenomenaDNANanotechnologyDNA

Identifiers

PMID17243754
PMCPMC2523266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.