ArticleNature cell biology2007
Control of local actin assembly by membrane fusion-dependent compartment mixing.
Article in Nature cell biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 70 citations in OpenAlex.
- Patterning of the cell cortex by Rho GTPases.Nature reviews. Molecular cell biology · 2024Review
- Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis.The Journal of cell biology · 2023Article
- A localized calcium transient and polar body abscission.Cell cycle (Georgetown, Tex.) · 2022Article
- Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling.The Journal of cell biology · 2022Article
- Exocytosis by vesicle crumpling maintains apical membrane homeostasis during exocrine secretion.Developmental cell · 2021Article
- Axon growth and synaptic function: A balancing act for axonal regeneration and neuronal circuit formation in CNS trauma and disease.Developmental neurobiology · 2020Review
- Actin and Myosin in Non-Neuronal Exocytosis.Cells · 2020Review
- Aurora kinase inhibitor tozasertib suppresses mast cell activation in vitro and in vivo.British journal of pharmacology · 2020Article
- Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases.eLife · 2019Article
- Interaction of microtubules and actin during the post-fusion phase of exocytosis.Scientific reports · 2019Article
- Coptisine Suppresses Mast Cell Degranulation and Ovalbumin-Induced Allergic Rhinitis.Molecules (Basel, Switzerland) · 2018Article
- Cellular mechanisms and signals that coordinate plasma membrane repair.Cellular and molecular life sciences : CMLS · 2018Review
- Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade bodies.Journal of thrombosis and haemostasis : JTH · 2018Article
- Living Xenopus oocytes, eggs, and embryos as models for cell division.Methods in cell biology · 2018Article
- Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules.Nature communications · 2017Article
- Membrane dynamics during cellular wound repair.Molecular biology of the cell · 2016Article
- Orchestrated content release from Drosophila glue-protein vesicles by a contractile actomyosin network.Nature cell biology · 2016Article
- Arp2/3-mediated F-actin formation controls regulated exocytosis in vivo.Nature communications · 2015Article
- Imaging membrane remodeling during regulated exocytosis in live mice.Experimental cell research · 2015Review
- Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles.Journal of cell science · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Local actin assembly is associated with sites of exocytosis in processes ranging from phagocytosis to compensatory endocytosis. Here, we examine whether the trigger for actin-coat assembly around exocytosing Xenopus egg cortical granules is 'compartment mixing'--the union of the contents of the plasma membrane with that of the secretory granule membrane. Consistent with this model, compartment mixing occurs on cortical granule-plasma membrane fusion and is required for actin assembly. Compartment mixing triggers actin assembly, at least in part, through diacylglycerol (DAG), which incorporates into the cortical granule membranes from the plasma membrane after cortical granule-plasma membrane fusion. DAG, in turn, directs long-term recruitment of protein kinase Cbeta (PKCbeta) to exocytosing cortical granules, where it is required for activation of Cdc42 localized on the cortical granules. The results demonstrate that mixing of two membrane compartments can direct local actin assembly and indicate that this process is harnessed during Xenopus egg cortical granule exocytosis to drive compensatory endocytosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.