ArticleEukaryotic cell2007
Aspergillus nidulans Dis1/XMAP215 protein AlpA localizes to spindle pole bodies and microtubule plus ends and contributes to growth directionality.
Article in Eukaryotic cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Dynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress inMolecular & cellular proteomics : MCP · 2020Article
- The Dis1/Stu2/XMAP215 Family GeneFrontiers in microbiology · 2020Article
- Fungal Morphogenesis, from the Polarized Growth of Hyphae to Complex Reproduction and Infection Structures.Microbiology and molecular biology reviews : MMBR · 2018Review
- Dynamics of Actin Cables in Polarized Growth of the Filamentous Fungus Aspergillus nidulans.Frontiers in microbiology · 2016Article
- Superresolution microscopy reveals a dynamic picture of cell polarity maintenance during directional growth.Science advances · 2015Article
- The role of +TIPs in directional tip expansion.Molecular microbiology · 2014Article
- The cell-end marker TeaA and the microtubule polymerase AlpA contribute to microtubule guidance at the hyphal tip cortex of Aspergillus nidulans to provide polarity maintenance.Journal of cell science · 2013Article
- The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics.Molecular biology of the cell · 2011Article
- Structural mutants of the spindle pole body cause distinct alteration of cytoplasmic microtubules and nuclear dynamics in multinucleated hyphae.Molecular biology of the cell · 2010Article
- GTP is required for the microtubule catastrophe-inducing activity of MAP200, a tobacco homolog of XMAP215.Plant physiology · 2009Article
- The cell end marker protein TeaC is involved in growth directionality and septation in Aspergillus nidulans.Eukaryotic cell · 2009Article
- The Aspergillus nidulans kinesin-3 UncA motor moves vesicles along a subpopulation of microtubules.Molecular biology of the cell · 2009Article
- Apical sterol-rich membranes are essential for localizing cell end markers that determine growth directionality in the filamentous fungus Aspergillus nidulans.Molecular biology of the cell · 2008Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The dynamics of cytoplasmic microtubules (MTs) is largely controlled by a protein complex at the MT plus end. In Schizosaccharomyces pombe and in filamentous fungi, MT plus end-associated proteins also determine growth directionality. We have characterized the Dis1/XMAP215 family protein AlpA from Aspergillus nidulans and show that it determines MT dynamics as well as hyphal morphology. Green fluorescent protein-tagged AlpA localized to MT-organizing centers (centrosomes) and to MT plus ends. The latter accumulation occurred independently of conventional kinesin or the Kip2-familiy kinesin KipA. alpA deletion strains were viable and only slightly temperature sensitive. Mitosis, nuclear migration, and nuclear positioning were not affected, but hyphae grew in curves rather than straight, which appeared to be an effect of reduced MT growth and dynamics.
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